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Appearance of prominent milia as secondary lesions during recovery of refractory bullous pemphigoid: a case report |
Li-Wen Zhang1, Lin Li1, Tao Chen1*, Wen-Ju Wang1, Li-Xin Fu1, Lin He2 |
1Department of Dermatovenereology, Chengdu Second People’s Hospital, Chengdu, Sichuan 610017, China.
2Department of Pathology, Chengdu Second People’s Hospital, Chengdu, Sichuan 610017, China. |
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Abstract Introduction
Bullous pemphigoid (BP) is an autoimmune blistering disease that affects patients of advanced age. BP is characterized clinically by tense bullae on the extremities and trunk, histopathologically by subepi-dermal blisters with eosinophilic infiltration, and immunologically by autoantibodies to BP180 and BP230. Direct immunofluorescence of perilesional skin shows depositions of IgG and C3 in the basement membrane zone[1]. BP rarely shows prominent milia formation, which is a hallmark of epidermolysis bullosa acquisita. We herein describe a 53-year-old man with refractory BP showing numerous milia during recovery.
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Received: 30 August 2018
Published: 15 January 2019
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Fund:This study was supported by Sichuan Province Medical Innovation Project for Youths (No.Q15003) and Chengdu Technological-Benevolent Project (No.2015-HM01-00095-SF). |
Corresponding Authors:
Dr. Tao Chen
E-mail: 13980427003@163.com
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