国际皮肤性病学杂志    2005 31 (5): 288-290   ISSN: 2096-5540  CN: 32-1880/R   HLA、HCR、CDSN基因在银屑病中的研究进展 吴丽峰, 普雄明 新疆维吾尔自治区人民医院皮肤科, 乌鲁木齐830001 收稿日期 2004-12-07  修回日期 null  网络版发布日期 null 参考文献  [1] Enerback C, Nilsson S, Enlund F, et al. Stronger association with HLA-Cw6 than with corneodesmosin (S-gene) polymorphisms in Swedish psoriasis patients. Arch Dermatol Res, 2000, 292:525. [2] Kundakci N, Oskay T, Olmez U,et al. Association of psoriasis vulgaris with HLA class Ⅰ and class Ⅱ antigens in the Turkish population, according to the age at onset. Int J Dermatol, 2002, 41:345. [3] Luszczek W, Kubicka W, Cislo M, et al. Strong association of HLA-Cw6 allele with juvenile psoriasis in Polish patients. Immunol Lett, 2003, 85:59-64. [4] Schmitt-Egenolf M, Eiermann TH, Boehncke WH, et al. Familial juvenile onset psoriasis is associated with the human leukocyte antigen (HLA) class Ⅰ side of the extended haplotype Cw6-B57-DRB1*0701-DQA1*0201-DQB1*0303:a population- and familybased study. J Invest Dermatol, 1996, 106:711-714. [5] Gonzalez S, Martinez-Borra J, Del Rio JS, et al. The OTF3 gene polymorphism confers susceptibility to psoriasis independent of the association of HLA-Cw*0602. J Invest Dermatol, 2000, 115:824. [6] Kastelan M, Gruber F, Cecuk-Jelicic E, et al. A new extended haplotype Cw*0602-B57-DRB1*0701-DQA1*0201-DQB1*0201 associated with psoriasis in the Croatian population. Clin Exp Dermatol, 2003, 28:200-202. [7] Fatma OS, Sarper DA, Dilek E, et al. HLA-DRB1 association in Turkish psoriasis vulgaris patients. Swiss Med Wkly, 2003, 133:541-543. [8] Chang YT, Tsai SF, Lee DD, et al. A study of candidate genes for psoriasis near HLA-C in Chinese patients with psoriasis. Br J Dermatol, 2003, 148:418--423. [9] Wei S, Gao M, Zhang X, et al. Study of the association between HLA-DQA1 alleles and environmental factors in psoriasis.Zhonghua Liu Xing Bing Xue Za Zhi, 2002, 23:445-448. [10] Zhang XJ, Zhang AP, Yang S, et al. Association of HLA class Ⅰ alleles with psoriasis vulgaris in southeastern Chinese Hans. J Dermatol Sci, 2003, 33:1-6. [11] Asumalahti K, Laitinen T, Itkonen-Vatjus R,et al. A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated susceptibility allele. Hum Mol Genet, 2000, 9:1533-1542. [12] Barker JN. Genetic aspects of psoriasis. Clin Exp Dermatol, 2001,26:321-325. [13] Asumalahti K, Veal C, Laitinen T, et al. Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus. Hum Mol Genet, 2002, 11:589-597. [14] Suomela S, Elormaa O, Asumalahti K, et al. HCR, a candidate gene for psoriasis, is expressed differently in psoriasis and other hyperproliferative skin disorders and is downregulated by interferon-gamma in keratinocytes. J Invest Dermatol, 2003, 121:1360-1364. [15] Chang YT, Shiao YM, Chin PJ, et al. Genetic polymorphisms of the HCR gene and a ge uomic segment in close proximity to HLA-C are associated with patients with psoriasis in Taiwan. Br J Dermatol,2004, 150:1104-1111. [16] O'Brien KP, Holm SJ, Nilsson S, et al. The HCR gene on 6p21 is unlikely to be a psoriasis susceptibility gene. J Invest Dermatol,2001, 116:750-754. [17] Allen MH, Veal C, Faassen A, et al. A non-HLA gene within the MHC in psoriasis. Lancet, 1999, 353:1589-1590, [18] Capon F, Toal IK, Evans JC, et al. Haplotype analysis of distantly related populations implicates corneodesmosin in psoriasis susceptibility. J Med Genet, 2003, 40:447-452. [19] Schmitt-Egenolf M, Windemuth C, Hennies HC, et al. Comparative association analysis reveals that corneodesmosin is more closely associated with psoriasis than HLA-Cw*0602-B*5701 in German families. Tissue Antigens, 2001, 57:440-446. [20] Hui J, Oka A, Tamiya G,et al. Corneodesmosin DNA polymorphisms in MHC haplotypes and Japanese patients with psoriasis. Tissue Antigens, 2002, 60:77-83. [21] Romphruk AY, Oka A, Romphruk A, et al. Corneodesmosin gene:no evidence for PSORS 1 gene in North-eastern Thai psoriasis patients. Tissue Antigens, 2003, 62:217-224. [22] Sagoo GS, Cork MJ, Patel R, et al. Genome-wide studies of psoriasis susceptibility loci:a review. J Dermatol Sci, 2004, 35:171-179. 通讯作者: