国际皮肤性病学杂志    2007 33 (6): 369-371   ISSN: 2096-5540  CN: 32-1880/R   特应性皮炎瘙痒机制的研究进展 祝青1, 刁庆春2, 白晋1 1. 重庆医科大学生物医学工程系、医学超声工程研究所, 400016; 2. 重庆市第一人民医院皮肤科 收稿日期 2007-03-02  修回日期 null  网络版发布日期 null 参考文献  [1] Schmelz M,Hilliges M,Schmidt R,et al.Active"itch fibers"in chronic pruritus.Neurology,2003,61(4):564-566. [2] Ikoma A,Handwerker H,Miyachi Y,et al.Electrically evoked itch in humans.Pain,2005,113(1-2):148. [3] Schmelz M.A neural pathway for itch.Nat Neurosci,2001,4(1):9-10. [4] Moehizuki H,Tashiro M,Kano M,et al.Imaging of central itch modulation in the human brain using positron emission tomography.Pain,2003,105(1-2):339-346. [5] Walter B,Sadlo MN,Kupfer J,et al.Brain activation by hisfamine prick test-induced itch.J Invest Dermatol,2005,125(2):380-382. [6] Stander S,Schmelz M,Metze D,et al.Distribution of cannabinoid receptor 1(CB1)and 2(CB2)on sensory nerve fibers and adnexal structures in human skin.J Dermatol Sci,2005,38(3):177-188. [7] Toyoda M,Nakarnura M,Makino T,et al.Nerve growth factor and substance P are useful plasma markers of disease activity in atopic dermatitis.Br J Dermatol,2002,147(1):71-79. [8] Steinhoff M,Stander S,Seeliger S,et al.Modern aspects of cutaneous neurogenic inflammation.Arch Dermatol,2003,139(11):1479-88. [9] Roosterman D,Cottrell GS,Schmidlin F,et al.Recycling and resensitization of the neurokinin 1 receptor.Influence of agonist concentration and Rab GTPases.J Biol Chem,2004,279(29):30670-30679. [10] Tanaka A,Matsuda H.Expression of nerve growth factor in itchy skins of atopic NC/NgaTnd mice.J Vet Med Sci,2005,67(9):915-919. [11] Matsushima H,Hayashi S,Shimada S.Skin scratching switches immune responses from Th2 to Th1 type in epieutaneously immunized mice.J Dermatol Sci,2003,32(3):223-230. [12] Heyer GR,Hornstein OP.Recent studies of cutaneous nociception in atopic and non-atopic subjects.J Dermatol,1999,26(2):77-86. [13] Rukwied R,Lischetzki G,McGlone F,et al.Mast cell mediators other than histamine induce pruritus in atopic dermatitis patients:a dermal microdialysis study.Br J Dermatol,2000,142(6):1114-1120. [14] Yosipovitch G,Fleischer A.Itch associated with skin disease:advances in pathophysiology and emerging therapies.Am J Clin Dermatol,2003,4(9):617-622. [15] Bigliardi-Qi M,Lipp B,Sumanovski LT,et al.Changes of epidermal mu-opiate receptor expression and nerve endings in chronic atopic dermatitis.Dermatology,2005,210(2):91-99. [16] Bell JK,McQueen DS,Rces JL.Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice.Br J Pharmacol,2004,142(2):374. [17] Steinhoff M,Neisius U,Ikoma A,et al.Proteinasc-activated receptor-2 mediates itch:a novel pathway for pruritus in human skin.J Neurosci,2003,23(15):6176-6180. [18] Dillon SR,Sprecher C,Hammond A,et al.Interleukin 31,a cytokine produced by activated T cells,induces dermatitis in mice.Nat Immunol,2004,5(7):752-760. [19] Sonkoly E,Muller A,Lauerma AI,et al.IL-31:a new link between T cells and pruritus in atopic skin inflammation.J Allergy Clin Immunol,2006,117(2):411-417. [20] Neisius U,Olsson R,Rukwied R,et al.Prostaglandin E2 induces vasodilation and pruritus,but no protein extravasation in atopic dermatitis and controls.J Am Acad Dermatol,2002,47(1):28-32. [21] Hashimoto Y,Arai I,Tanaka M,et al.Prostaglandin D2 inhibits IgE-mediated scratching by suppressing histamine release from mast cells.J Pharmacol Sci,2005,98(1):90-93. [22] Abeck D,Andersson T,Grosshans E,et al.Topical application of a platelet-activating factor(PAF)antagonist in atopic dermatitis.Acta Derm Venereol,1997,77(6):449-451. 通讯作者: