国际皮肤性病学杂志    2007 33 (5): 275-277   ISSN: 2096-5540  CN: 32-1880/R   基因芯片与银屑病治疗 刘雅妍1, 顾军2 1. 湖南省株洲市一医院皮肤科 412000; 2. 第二军医大学长海医院皮肤科 收稿日期 2007-01-30  修回日期 null  网络版发布日期 null 参考文献  [1] Zhou X,Krueger JG,Kao MC,et al.Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array.Physiol Genomics,2003,13 (1):69-78. [2] Nomura I,Gao B,Boguniewicz M,et al.Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis:a gene microarray analysis.J Allergy Clin Immunol,2003,112(6):1195-1202. [3] Ono SJ,Nakamura T,Miyazaki D,et al.Chemokines:roles in leukocyte development,trafficking,and effector function.J Allergy Clin Immunol,2003,111(6):1185-1200. [4] Bonifati C,Mussi A,D'Auria L,et al.Spontaneous release of leukemia inhibitory factor and oncostatin-M is increased in supernatants of short-term organ cultures from lesional psoriatic skin.Arch Dermatol Res,1998,290 (1-2):9-13. [5] Finelt N,Gazel A,Gorelick S,et al.Transcriptional responses of human epidermal keratinocytes to Oncostatin-M.Cytokine,2005,31(4):305-313. [6] Gazel A,Rosdy M,Bertino B,et al.A characteristic subset of psoriasis-associated genes is induced by oncostatin-M in reconstituted epidermis.J Invest Dermatol,2006,126 (12):2647-2657. [7] Bowcock AM,Shannon W,Du F,et al.Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies.Hum Mol Genet,2001,10 (17):1793-1805. [8] Oestreicher JL,Walters IB,Kikuchi T,et al.Molecular classification of psoriasis disease-associated genes through pharmacogenomic expression profiling.Pharmacogenomics J,2001,1(4):272-287. [9] Batliwalla FM,Li W,Ritchlin CT,et al.Microarray analyses of peripheral blood cells identifies unique gene expression signature in psoriatic arthritis.Mol Med,2005,11 (1-12):21-29. [10] Baron JM,Heise R,Blaner WS,et al.Retinoic acid and its 4-oxo metabolites are functionally active in human skin cells in vitro.J Invest Dermatol,2005,125 (1):143-153. [11] Lu J,Goldstein KM,Chen P,et al.Transcriptional profiling of keratinocytes reveals a vitamin D-regulated epidermal differentiation network.J Invest Dermatol,2005,124 (4):778-785. [12] Ishida-Yamamoto A,Senshu T,Takahashi H,et al.Decreased deiminated keratin K1 in psoriatic hyperproliferative epidermis.J Invest Dermatol,2000,114 (4):701-705. [13] Banno T,Gazel A,Blumenberg M.Effects of tumor necrosis factor-alpha (TNF alpha) in epidermal keratinocytes revealed using global transcriptional profiling.J Biol Chem,2004,279(31):32633-32642. [14] Becker B,Vogt T,Landthaler M,et al.Detection of differentially regulated genes in keratinocytes by cDNA array hybridization:Hsp27 and other novel players in response to artificial ultraviolet radiation.J Invest Dermatol,2001,116(6):983-988. [15] Rappersberger K,Komar M,Ebelin ME,et al.Pimecrolimus identifies a common genomic anti-inflammatory profile,is clinically highly effective in psoriasis and is well tolerated.J Invest Dermatol,2002,119 (4):876-887. 通讯作者: 顾军,email:gujun79@163.com