国际皮肤性病学杂志    2006 32 (6): 400-402   ISSN: 2096-5540  CN: 32-1880/R   静脉注射免疫球蛋白治疗自身免疫性大疱病的现状 袁艳霞, 林麟 中国医学科学院、中国协和医科大学皮肤病研究所, 南京210042 收稿日期 2006-04-26  修回日期 null  网络版发布日期 null 参考文献  [1] Herzog S,Schmidt E,Goebeler M,et al.Serum levels of autoantibodies to desmoglein 3 in patients with therapy-resistant pemphigus vulgaris successfully treated with adjuvant intravenous immunoglobulins.Acta Derm Venereol,2004,84:48-52. [2] Jolles S.A review of high-dose intravenous immunoglobulin (hdIVIg) in the treatment of the autoimmune blistering disorders.Clin Exp Dermatol,2001,26:127-131. [3] Ahmed AR.Intravenous immunoglobulin therapy for patients with bullous pemphigoid unresponsive to conventional immunosuppressive treatment.J Am Acad Dermatol,2001,45:825-835. [4] Ahmed AR,Colon JE.Comparison between intravenous immunoglobulin and conventional immunosuppressive therapy regimens in patients with severe oral pemphigoid:effects on disease progression in patients nonresponsive to dapsone therapy.Arch Dermatol,2001,137:1181-1189. [5] Sami N,Bhol KC,Ahmed AR.Treatment of oral pemphigoid with intravenous immunoglobulin as monotherapy.Long-term follow-up:influence of treatment on antibody titres to human alpha6integrin.Clin Exp Immunol,2002,129:533-540. [6] Ahmed AR.Intravenous immunoglobulin therapy in the treatment of patients with pemphigus vulgaris unresponsive to conventional immunosuppressive treatment.J Am Acad Dermatol,2001,45:679-690. [7] Sami N,Bhol KC,Ahmed RA.Influence of intravenous immunoglobulin therapy on autoantibody titers to desmoglein 3 and desmoglein 1 in pemphigus vulgaris.Eur J Dermatol,2003,13:377-381. [8] Sami N,Ali S,Bhol KC,et al.Influence of intravenous immunoglobulin therapy on autoantibody titres to BP Agl and BP Ag2 in patients with bullous pemphigoid.J Eur Acad Dermatol Venereol,2003,17:641-645. [9] Ahmed AR,Dahl MV.Consensus statement on the use of intravenous immunoglobulin therapy in the treatment of autoimmune mucocutaneous blistering diseases.Arch Dermatol,2003,139:1051. [10] Mydlarski PR,Mittmann N,Shear NH.Intravenous immunoglobulin:use in dermatology.Skin Therapy Lett,2004,9:1-6. [11] Sheehan DJ,Lesher JL Jr.Deep venous thrombosis after high-dose intravenous immunoglobulin in the treatment ofpemphigus vulgaris.Cutis,2004,73:403-406. [12] Bystryn JC,Rudolph JL.IVI g TREATMENT OF PEMPHIGUS:how it works and how to use it.J Invest Dermatol,2005,125:1093. [13] Li N,Zhao M,Hilario-Vargas J,et al.Complete FcRn dependence for intravenous Ig therapy in autoimmune skin blistering diseases.JClin Invest,2005,115:3440-3450. [14] Mimouni D,Blank M,Ashkenazi L,et al.Protective effect of intravenous immunoglobulin (MG) in an experimental model of pemphigus vulgaris.Clin Exp Immunol,2005,142:426-432. [15] Bhol KC,Desai A,Kumari S,et al.Pemphigus vulgaris:the role of IL-1 and IL-1 receptor antagonist in pathogenesis and effects of intravenous immunoglobulin on their production.Clin Immunol,2001,100:172-180. [16] Wang X,Bregegere F,Frusic-Zlotkin M,et al.Possible apoptotic mechanism in epidermal cell acantholysis induced by pemphigus vulgaris autoimmunoglobulins.Apoptosis,2004,9:131-143. [17] Arredondo J,Chernyavsky AI,Karaouni A,et al.Novel mechanisms of target cell death and survival and of therapeutic action of IVIg in Pemphigus.Am J Pathol,2005,167:1531-1544. 通讯作者: