国际皮肤性病学杂志    2006 32 (6): 353-355   ISSN: 2096-5540  CN: 32-1880/R   凋亡物质清除障碍与系统性红斑狼疮 王庭辉, 郑敏 浙江大学医学院附属第二医院皮肤科, 杭州310009 收稿日期 2006-03-21  修回日期 null  网络版发布日期 null 参考文献  [1] Reefman E,Limburg PC,Kallenberg CG,et al.Apoptosis in human skin:role in pathogenesis of various diseases and relevance for therapy.Ann N Y Acad Sci,2005,1051:52-63. [2] Tas SW,Quartier P,Botto M,et al.Macrophages from patients with SLE and rheumatoid arthritis have defective adhesion in vitro,while only SLE macrophages have impaired uptake of apoptotic cells.Ann Rheum Dis,2006,65:216-221. [3] Franz S,Gaipl U,Appelt U,et al.The role of a defective clearance in the pathogenesis of systemic lupus erythematosus.Arthritis Res Ther,2004,6:S34. [4] Botto M,Dell'Agnola C,Bygrave AE,et al.Homozygous Clq deficiency causes glomerulonephritis associated with multiple apoptotic bodies.Nat Genet,1998,19:56-59. [5] Stone NM,Williams A,Wilkinson JD,et al.Systemic lupus erythematosus with Clq deficiency.Br J Dermatol.2000,142:521-524. [6] Horák P,Hermanova Z,Zadrazil J,et al.Clq complement component and antibodies reflect SLE activity and kidney involvement.Clin Rheumatol,2006,25:532-536. [7] Ittiprasert W,Kantachuvesiri S,Pavasuthipaisit K,et al.Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.J Autoimmun,2005,25:77-84. [8] Man XY,Luo HR,Li XP,et al.Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping:association with systemic lupus erythematosus in southwest Han Chinese.Ann Rheum Dis,2003,62:71-73. [9] de Carvalho Lins CE,Pereira Crott LS,Teixeira JE,et al.Reduced erythrocyte complement receptor type 1 in systemic lupus erythematosus is related to a disease activity index and not to the presence or severity of renal disease.Lupus,2004,13:517-521. [10] Arora V,Verma J,Dutta R,et al.Reduced complement receptor 1 (CR1,CD35) transcription in systemic lupus erythematosus.Mol Immunol,2004,41:449-456. [11] Sallai K,Nagy E,Derfalvy B,et al.Antinucleosome antibodies and decreased deoxyribonuclease activity in sera of patients with systemic lupus erythematosus.Clin Diagn Lab Immunol,2005,12:56-59. [12] Yasutomo K,Horiuchi T,Kagami S,et al.Mutation of DNASE1 in people with systemic lupus erythematosus.Nat Genet,2001,28:313-314. [13] Shin HD,Park BL,Kim LH,et al.Common DNase I polymorphism associated with autoantibody production among systemic lupus erythematosus patients.Hum Mol Genet,2004,13:2343-2350. [14] BodanoA,GonzalezA,Ferreiros-VidalI,et al.Association of a non-synonymous single-nucleotide polymorphism of DNASEI with SLE susceptibility.Rheumatology (Oxford),2006,45:819-823. [15] BickerstaffMC,Botto M,Hutchinson WL,et al.Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity.Nat Med,1999,5:694-697. [16] Rodriguez W,Mold C,Mamell LL,et al.Prevention and reversal of nephritis in MRL/lpr mice with a single injection of C-reactive protein.Arthritis Rheum,2006,54:325-335. [17] Sjowall C,Bengtsson AA,Sturfelt G,et al.Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus.Arthritis Res Ther,2004,6:R87-94. [18] Williams RC Jr,Harmon ME,Burlingame R,et al.Studies of serum C-reactive protein in systemic lupus erythematosus.J Rheumatol,2005,32:454-461. [19] Wu Y,Singh S,Georgescu MM,et al.A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells.J Cell Sci,2005,118(Pt 3):539-553. [20] Quartier P,Potter PK,Ehrenstein MR,et al.Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophages in vitro.Eur J Immunol,2005,35:252-260. 通讯作者: 郑敏,email:zhengmin@medmail.com.cn