国际皮肤性病学杂志    2006 32 (4): 235-237   ISSN: 2096-5540  CN: 32-1880/R  

低氧诱导因子-1与皮肤的相关研究
戴叶芹, 范卫新
南京医科大学第一附属医院皮肤科, 210029
收稿日期 2005-11-30  修回日期 null  网络版发布日期 null
参考文献  [1] Vincent KA,Shyu KG,Luo Y,et al.Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-lalpha/VP16 hybrid transcription factor.Circulation,2000,102:2255-2261.
[2] Sutter CH,Laughner E,Semenza GL.Hypoxia-inducible factor 1 alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations.Proc Natl Acad Sci U S A,2000,97:4748-4753.
[3] Richard DE,Berra E,Pouyssegur J.Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1 alpha in vascular smooth muscle cells.J Biol Chem,2000,27:26765-26771.
[4] Zhong H,De Marzo AM,Laughner E,et al.Overexpression of hypoxia-inducible factor 1 alpha in common human cancers and their metastases.Cancer Res,1999,59:5830-5835.
[5] Elson DA,Ryan HE,Snow JW,et al.Coordinate up-regulation of hypoxia inducible factor (HIF)-1 alpha and HIF-1 target genes during multi-stage epidermal carcinogenesis and wound healing.Cancer Res,2000,60:6189-6195.
[6] Scheid A,Wenger RH,Christina H,et al.Hypoxia-regulated gene expression in fetal wound regeneration and adult wound repair.Pediatr Surg Int,2000,16:232-236.
[7] Zhang Q,Wu Y,Chau CH,et al.Crosstalk of hypoxia-mediated signaling pathways in upregulating plasminogen activator inhibitor-1 expression in keloid fibroblasts.J Cell Physiol,2004,199:89-97.
[8] Kwon YW,Kwon KS,Moon HE,et al.Insulin-like growth factor-Ⅱ regulates the expression of vascular endothelial growth factor by the human keratinocyte cell line HaCaT.J Invest Dermatol,2004,123:152-158.
[9] Giatromanolaki A,Arvanitidou V,Hatzimichael A,et al.The HIF-2 alpha/VEGF pathway activation in cutaneous capillary haemangiomas.Pathology,2005,37:149-151.
[10] Arrais-Silva WW,Paffaro VA Jr,Yamada AT,et al.Expression of hypoxia-inducible factor-1 alpha in the cutaneous lesions of BALB/c mice infected with Leishmania amazonensis.Exp Mol Pathol,2005,78:49-54.
[11] Distler K.Hypoxia and angiogenesis in rheumatic diseases.Z Rheumatol,2003,62(Suppl 2):Ⅱ43-45.
[12] Elson DA,Thurston G,Huang LE,et al.Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1 alpha.Genes Dev,2001,15:2520-2532.
[13] Linden T,Katschinski DM,Eckhardt K,et al.The antimycotic ciclopirox olamine jnduces HIF-1 alpha stability,VEGF expression,and angiogenesis.FASEB J,2003,17:761-763.
[14] Vihanto MM,Plock J,Erni D,et al.Hypoxia up-regulates expression of Eph receptors and ephrins in mouse skin.FASEB J,2005,19:1689-1691.

通讯作者: