国际皮肤性病学杂志    2006 32 (3): 147-149   ISSN: 2096-5540  CN: 32-1880/R   H1抗组胺药物研究进展 万学峰, 惠艳 新疆医科大学第一临床医院皮肤科 乌鲁木齐 830054 收稿日期 2005-09-26  修回日期 null  网络版发布日期 null 参考文献  [1] Fujikura T,Shimosawa T,Yakuo I.Regulatory effect of histamine H1 receptor antagonist on the expression of messenger RNA encoding CC chemokines in the human nasal mucosa.J Allergy Clin Immunol,2001,107:123-128. [2] Banu Y,Watanabe T.Augmentation of antigen receptor-mediated responses by histamine H1 receptor signaling.J Exp Med,1999,189:673-682. [3] Yanai K,Son LZ,Endou M,et al.Targeting disruption of histamine H1 receptors in mice:behavioral and neurochemical characterization.Life Sci,1998,62:1607-1610. [4] Shamsi Z,Hindmarch I.Sedation and antihistamines:a review of inter-drug differences using proportional impairment ratios.Hum Psychopharmacol,2000,15(Suppl 1):S3-S30. [5] Reimers A,Hari Y,Muller U.Reduction of side-effects from ultrarush immunotherapy with honeybee venom by pretreatment with fexofenadine:a double-blind,placebo-controlled trial.Allergy,2000,55:484-488. [6] Kawashima M,Tango T,Noguchi T,et al.Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized,multicentre,double-blind,placebo-controlled,parallel-group study.Br J Dermatol,2003,148:1212-1221. [7] Diepgen TL.Long-term treatment with cetirizine of infants with atopic dermatitis:a multi-country,double-blind,randomized,placebo-controlled trial (the ETAC trial) over 18 months.Pediatr Allergy Immuno,2002,13:278-286. [8] Karppinen A,Kautiainen H,Petman L,et al.Comparison of cetirizine,ebastine and loratadine in the treatment of immediate mosquito-bite allergy.Allergy,2002,57:534-537. [9] Timmerman H.Factors involved in the absence of sedative effects by the second-generation antihistamines.Allergy,2000,55(Suppl 60):5-10. [10] Chishty M,Reichel A,Siva J,et al.Affinity for the P-glycoprotein efflux pump at the blood-brain barrier may explain the lack of CNS side-effects of modem antihistamines.J Drug Target,2001,9:223-228. [11] Chen C,Hanson E,Watson JW,et al.P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists.Drug Metab Dispos,2003,31:312-318. [12] Cobb DB,Watson WA,Fernandez MC.High-dose loratadine exposure in a six-year-old child.Vet Hum Toxicol,2001,43:163-164. [13] Spiller HA,Villalobos D,Benson BE,et al.Retrospective evaluation of cetirizine (zyrtec) ingestion.J Toxicol Clin Toxicol,2002,40:525-526. [14] Weiler JM,Bloomfield JR,Woodworth GG,et al.Effects of fexofenadine,diphenhydramine,and alcohol on driving performance.A randomized,placebo-controlled trial in the Iowa driving simulator.Ann Intern Med,2000,132:354-363. [15] De Bruin ML,van Puijenbroek EP,Egberts AC,et al.Non-sedating antihistamine drugs and cardiac arrhythmias --biased risk estimates from spontaneous reporting systems? Br J Clin Pharmacol,2002,53:370-374. 通讯作者: