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国际皮肤性病学杂志 2006 32 (2): 99-101 ISSN: 2096-5540 CN: 32-1880/R |
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白念珠菌分泌型天冬氨酸蛋白酶研究进展 |
王凯丽, 张宏 |
暨南大学附属第一医院皮肤科 广州 510632 |
收稿日期 2005-06-13 修回日期 null 网络版发布日期 null |
参考文献 [1] Koelsch G,Tang J,Loy JA,et al.Enzymic characteristics of secreted aspartic proteases of Candida albicans.Biochim Biophys Acta,2000,1480:117-131. [2] Ripeau JS,Fiorillo M,Aumont F,et al.Evidence for differential expression of Candida albicans virulence genes during oral infection in intact and human immunodeficiency virus type 1-transgenic mice.J Infect Dis,2002,185:1094-1102. [3] Naglik JR,Rodgers CA,Shirlaw P J,et al.Differential expression of Candida albicans secreted aspartyl proteinase and phospholipase B genes in humans correlates with active oral and vaginal infections.J Infect Dis,2003,188:469-479. [4] Felk A,Kretschmar M,Albrecht A,et al.Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4to Sap6 are required for the invasion ofparenchymal organs.Infect Immun,2002,70:3689-3700. [5] Staib P,Kretschmar M,Nichterlein T,et al.Host versus in vitro signals and intrastrain allelic differences in the expression of a Candida albicans virulence gene.Mol Microbiol,2002,44:1351-1366. [6] Tavanti A,Pardini G,Campa D,et al.Differential expression of secretory aspartyl proteinase genes (SAP1-10) in oral Candida albicans isolates with distinct karyotypes.J Clin Microbiol,2004,42:4726-4734. [7] Chen YC,Wu CC,Chung WL,et al.Differential secretion of Sap4-6proteins in Candida albicans during hyphae formation.Microbiology,2002,148(Pt 11):3743-3754. [8] Korting HC,Hube B,Oberbauer S,et al.Reduced expression of the hyphal-independent Candida albicans proteinase genes SAP1 and SAP3 in the efgl mutant is associated with attenuated virulence during infection of oral epithelium.J Med Microbiol,2003,52 (Pt 8):623-632. [9] Staib P,Kretschmar M,Nichterlein T,et al.Transcriptional regulators Cphlp and Efglp mediate activation of the Candida albicans virulence gene SAP5 during infection.Infect Immun,2002,70:921-927. [10] Schweizer A,Rupp S,Taylor BN,et al.The TEA/ATTS transcription factor CaTeclp regulates hyphal development and virulence in Candida albicans.Mol Microbiol,2000,38:435-445. [11] Staib P,Binder A,Kretschmar M,et al.Teclp-independent activation of a hypha-associated Candida albicans virulence gene during infection.Infect Immun,2004,72:2386-2389. [12] Murad AM,d'Enfert C,Gaillardin C,et al.Transcript profiling in Candida albicans reveals new cellular functions for the transcriptional repressors CaTupl,CaMigl and CaNrgl.Mol Microbiol,2001,42:981-993. [13] Kitanovic A,Nguyen M,Vogl G,et al.Phosphatidylinositol 3-kinase VPS34 of Candida albicans is involved in filamentous growth,secretion of aspartic proteases,and intracellular detoxification.FEMS Yeast Res,2005,5:431-439. [14] Hube B,Naglik J.Candida albicans proteinases:resolving the mystery of a gene family.Microbiology,2001,147 (Pt 8):1997-2005. [15] Bektic J,Lell CP,Fuchs A,et al.HIV protease inhibitors attenuate adherence of Candida albicans to epithelial cells in vitro.FEMS Immunol Med Microbiol,2001,31:65-71. [16] Kretschmar M,Felk A,Staib P,et al.Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in mice.Microb Pathog,2002,32:61-70. |
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