国际皮肤性病学杂志    2006 32 (1): 54-56   ISSN: 2096-5540  CN: 32-1880/R   Th1/Th2细胞因子与生殖器疱疹关系的研究现状 朱小华, 徐金华 复旦大学附属华山医院皮肤科, 上海200040 收稿日期 2005-05-06  修回日期 null  网络版发布日期 null 参考文献  [1] Paul WE.Fundamental Inmunology.4th edit.USA:Lippincott Williams & Wilkins,1999.884-900. [2] Paul WE.Fundamental Immunology.4th edit.USA:Lippincott Williams & Wilkins,1999.765-767. [3] Wang JH,Layden TJ,Eckels DD.Modulation of the peripheral T-Cell response by CD4 mutants of hepatitis C virus:transition from a Th1 to a Th2 response.Hum Immunol,2003,64:662-673. [4] Bertoletti A,D'Elios MM,Boni C,et al.Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections.Gastroenterology,1997,112:193-199. [5] Scott M,Stites DP,Moscicki AB.Th1 cytokine patterns in cervical human papillomavirus infection.Clin Diagn Lab Immunol,1999,6:751-755. [6] El-Sherif AM,Seth R,Tighe PJ,et al.Quantitative analysis of IL-10 and IFN-gamma mRNA levels in normal cervix and human papillomavirus type 16 associated cervical precancer.J Pathol,2001,195:179-185. [7] Ramalingam S,Kannangai R,Vijayakumar TS,et al.Subtype & cytokine profiles of HIV infected individuals from south India.Indian J Med Res,2005,121:226-234. [8] 钱起丰,郭红卫.复发性生殖器疱疹患者外周血CD3+T细胞内细胞因子的检测.中华皮肤科杂志,2001,34:195-197. [9] Mezentseva MV,Narovlyansky AN,Scherbenko VE,et al.Analysis of the interferon status and cytokine profile in patients with genital herpes.Russ J Immunol,2002,7:167-174. [10] Singh R,Kumar A,Creery WD,et al.Dysregulated expression of IFN-gamma and IL-10 and impaired IFN-gamma-mediated responses at different disease stages in patients with genital herpes simplex virus-2 infection.Clin Exp Immunol,2003,133:97-107. [11] Shurshalina AV,Veryasov VN,Sukhikh GT.The ratio of cytokine levels in genital herpes during various phases of infection.Bull Exp Biol Med,2001,132:660-662. [12] Tanigawa M,Bigger JE,Kanter MY,et al.Natural killer cells prevent direct anterior-to-posterior spread of herpes simplex virus type I in the eye.Invest Ophthalmol Vis Sci,2000,41:132-137. [13] Lekstrom-Himes JA,LeBlane RA,Pesnicak L,et al.Gamma interferon impedes the establishment of herpes simplex virus type 1 latent infection but has no impact on its maintenance or reactivation in mice.J Virol,2000,74:6680-6683. [14] Eriksson K,Bellner L,Gorander S,et al.CD4(+) T-cell responses to herpes simplex virus type 2 (HSV-2) glycoprotein G are type specific and differ in symptomatic and asymptomatic HSV-2-infected individuals.J Gen Virol,2004,85:2139-2147. [15] Thebeau LG,Morrison LA.Mechanism of reduced T-cell effector functions and class-switched antibody responses to herpes simplex virus type 2 in the absence of B7 costimulation.J Virol,2003,77:2426-2435. [16] Xu M,Lepisto AJ,Hendricks RL.CD154 signaling regulates the Th1 response to herpes simplex virus-1 and inflammation in infected corneas.J Immunol,2004,173:1232-1239. [17] Yokota S,Yokosawa N,Okabayashi T,et al.Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.J Virol,2004,78:6282-6286. [18] Cao L,Martin A,Polakos N,et al.Stress causes a further decrease in immunity to herpes simplex virus-1 in immunocompromised hosts.J Neuroimmunol,2004,156:21-30. [19] Eo SK,Lee S,Kumaraguru U,et al.Immunopotentiation of DNA vaccine against herpes simplex virus via co-delivery of plasmid DNA expressing CCB7 ligands.Vaccine,2001,19:4685-4693. [20] Zhu M,Xu X,Liu H,et al.Enhancement of DNA vaccine potency against herpes simplex virus 1 by co-administration of an interleukin-18 expression plasmid as a genetic adjuvant.J Med Microbiol,2003,52:223-228. [21] Wu JJ,Huang DB,Tyring SK.Resiquimod:a new immune response modifier with potential as a vaccine adjuvant for Th1 immune responses.Antiviral Res,2004,64:79-83. [22] Mohamedi SA,Heath AW,Jennings R.Therapeutic vaccination against HSV-2:influence of vaccine formulation on immune responses and protection in mice.Vaccine,2000,18:1778-1792. [23] Mezentseva MV,Shcherbenko VE,Narovlianskii AN,et al.Features of interferon and cytokine production in genital herpes.Vopr Virusol,2003,48:33-37. [24] Wakabayashi H,Kurokawa M,Shin K,et al.Oral lactoferrin prevents body weight loss and increases cytokine responses during herpes simplex virus type 1 infection of mice.Biosci Biotechnol Biochem,2004,68:537-544. [25] Al-Khatib K,Campbell IL,Carr DJ.Resistance to ocular herpes simplex virus type 1 infection in IL-12 transgenic mice.J Neuroimmunol,2002,132:41-48. 通讯作者: