国际皮肤性病学杂志    2005 31 (4): 226-228   ISSN: 2096-5540  CN: 32-1880/R   肠病性肢端皮炎的研究进展 任韵清, 杨森, 张学军 安徽医科大学皮肤病研究所、第一附属医院皮肤科, 合肥230022 收稿日期 2004-09-23  修回日期 null  网络版发布日期 null 参考文献  [1] Perafan-Riveros C, Franca LF, Alves AC,et al. Acrodermatitis enteropathica: case report and review of the literature. Pediatr Dermatol,2002, 19:426-431. [2] Sehgal VN, Jain S. Acrodermatitis enteropathica. Clin Dermatol,2000,18:745-748. [3] Marklova E. Microelements and inherited metabolic diseases. Acta Medica ( Hradec Kralove), 2002,45:129-133. [4] Rostan EF, DeBuys HV, Madey DL, et al. Evidence supporting zinc as an important antioxidant for skin. Int J Dermatol, 2002,41:606-611. [5] Ozkan S, Ozkan H, Fetil E, et al. Acrodermatitis enteropathica with Pseudomonas aeruginosa sepsis. Pediatr Dermatol, 1999, 16:444-447. [6] Grider A, Lin YF, Muga SJ. Differences in the cellular zinc content and 5'-nucleotidase activity of normal and acrodermatitis enteropathica (AE) fibroblasts. Biol Trace Elem Res, 1998,61:1-8. [7] Grider A, Mouat MF. The acrodermatitis enteropathica mutation affects protein expression in human fibroblasts: analysis by two-dimensional gel electrophoresis. J Nutr, 1998, 128:1311-1314. [8] Wang K, Pugh EW, Griffen S, et al. Homozygosity mapping places the acrodermatitis enteropathica gene on chromosomal region 8q24.3.Am J Hum Genet, 2001, 68:1055-1060. [9] Gaither LA, Eide DJ. The human ZIP1 transporter mediates zinc uptake in human K562 erythroleukemia cells. J Biol Chem, 2001,276:22258-22264. [10] Kury S, Dreno B, Bezieau S, et al. Identification of SLC39A4, a gene involved in acrodermatitis enteropathica. Nat Genet, 2002, 31:239-240. [11] Kury S, Kharfi M, Kamoun R, et al. Mutation spectrum of human SLC39A4 in a panel of patients with acrodermatitis enteropathica.Hum Mutat, 2003, 22:337-338. [12] Wang K, Zhou B, Kuo YM, et al. A novel member of a zinc transporter family is defective in acrodermatitis enteropathica. Am J Hum Genet, 2002, 71:66-73. [13] Nakano A, Nakano H, Nomura K, et al. Novel SLC39A4 mutations in acrodermatitis enteropathica. J Invest Dermatol, 2003, 120:963-966. [14] Gaither LA, Eide DJ. Eukaryotic zinc transporters and their regulation. Biometals, 2001, 14:251-270. [15] Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch,2004, 447:796-800. [16] Dufner-Beattie J, Wang F, Kuo YM, et al. The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice. J Biol Chem, 2003, 278:33474-33481. [17] Kim BE, Wang F, Dufner-Beattie J, et al. Zn2 +-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane. J Biol Chem, 2004, 279:4523-4530. [18] Dufner-Beattie J, Kuo YM, Gitschier J, et al. The adaptive response to dietary zinc in mice involves the differential cellular localization and zinc regulation of the zinc transporters ZIP4 and ZIP5. J Biol Chem,2004, 279:49082-49090. [19] Wang F, Kim BE, Dufner-Beattie J,et al. Acrodermatitis enteropathica mutations affect transport activity, localization and zinc-responsive trafficking of the mouse ZIP4 zinc transporter. Hum Mol Genet, 2004,13:563-571. [20] Huang L, Gitschier J. A novel gene involved in zinc transport is deficient in the lethal milk mouse. Nat Genet, 1997, 17:292-297. [21] Bleck O, Ashton GH, Mallipeddi R, et al. Genomic localization, organization and amplification of the human zinc transporter protein gene, ZNT4, and exclusion as a candidate gene in different clinical variants of acrodermatitis enteropathica. Arch Dermatol Res, 2001,293:392-396. [22] Kury S, Devilder MC, Avet-Loiseau H, et al. Expression pattern, genomic structure and evaluation of the human SLC30A4 gene as a candidate for acrodermatitis enteropathica. Hum Genet, 2001, 109:178-185. [23] Nakano A, Nakano H, Hanada K, et al. ZNT4 gene is not responsible for acrodermatitis enteropathica in Japanese families. Hum Genet,2002, 110:201-202. [24] Sandstrom B, Cederblad A, Lindblad BS, et al. Acrodermatitis enteropathica, zinc metabolism, copper status, and immune function. Arch Pediatr Adolesc Med, 1994, 148:980-985. 通讯作者: