国际皮肤性病学杂志    2004 30 (2): 117-119   ISSN: 2096-5540  CN: 32-1880/R   DNA错配修复基因在皮肤黑素瘤中的研究进展 张春梅, 李慎秋 华中科技大学同济医学院附属同济医院皮肤性病科, 武汉 430030 收稿日期 2003-05-12  修回日期 null  网络版发布日期 null 参考文献  [1] Bocker T, Barusevicius A, Snowden T, et al. hMSH5:a human MutS homologne that forms a novel heterodimer with hMSH4 and is expressed during spermatogenesis. Cancer Res, 1999, 59(4):816-822. [2] Paquis-Flucklinger V, Santucci-Darmanin S, Paul R, et al. Cloning and expression analysis of a meiosis-specific MutS homolog:the human MSH4 gene. Genomics, 1997, 44(2):188-194. [3] Karran P. Microsatellite instability and DNA mismatch repair in human cancer. Semin Cancer Biol, 1996, 7(1):15-24. [4] Crul M, Schellens. JH, Beijnen JH, et al. Cisplatin resistance and DNA repair. Cancer Treat Rev, 1997, 23(5-6):341-366. [5] Modrich P. Mismatch repair, genetic stability, and cancer, Science,1994, 266(5193):1959-1960. [6] Hussein MR, Roggero E, Sudilovsky EC, et al. Alterations of mismatch repair protein expression in benign melanbcytic nevi, melanocytic dysplastic nevi, and cutaneous malignant melanomas. Am J Dermatopathol, 2001, 23(4):308-314. [7] Korabiowska M, Brinck U, Dengler H, et al. Analysis of the DNA mismatch repair proteins expression in malignant melanomas. Anticancer Res, 2000, 20(6B):4499-4505. [8] Korabiowska M, Ruschenburg I, Schlott T, et al. Relation between DNA ploidy status and the expression of the DNA-mismatch repair genes MLH1 and MSH2 in cytological specimens of melanoma lymph node and liver metastases. Diagn Cytopathol, 2001, 24(3):157-162. [9] Korabiowska M, Tschemy M, Stachura J, et al. Relationship between DNA mismatch repair genes expression, Ku-genes expression and ploidy-related parameters in the progression of pigmented lesions of the skin. In Vivo, 2002, 16(5):317-321. [10] Aaltonen LA, Peltomaki P, Leach FS, et al. Clues to the pathogenesis of familial colorectal cancer. Science, 1993, 260(5109):812-816. [11] Bo1and CR. Roles of the DNA mismatch repair genes in colorectal tumorigenesis. Int J Cancer, 1996, 69(1):47-49. [12] Birindelli S, Tragni G, Bartoli C, et al. Detection of microsatellite alterations in the spectrum of melanocytic nevi in patients with or without individual or family history of melanoma. Int J Cancer, 2000, 86(2):255-261. [13] Tomlinson IP, Beck NE, Bodmer WF. Allele loss on chromosome 11 q and microsatellite instability in malignant melanoma. Eur J Cancer,1996, 32A(10):1797-1802. [14] Korabiowska M, Viehover M, Schlott T, et al. Relationship between DNA ploidy-related parameters and the deletions in mismatch repair genes MLH1 and MSH2 in lentigo maligna and malignant melanomas.Arch Dermatol Res, 2001,293(5):219-225. [15] Umar A, Buermeyer AB, Simon JA, et al. Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis. Cell,1996, 87(1):65-73. [16] Davis TW, Wilson-Van Patten C, Meyers M, et al. Defective expression of the DNA mismatch repair protein, MLHI, alters G2-M cell cycle checkpoint arrest following ionizing radiation. Cancer Res,1998, 58(4):767-778. [17] Hirose Y, Berger MS, Pieper RO. p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells. Cancer Res, 2001,61(5):1957-1963. 通讯作者: