国际皮肤性病学杂志    2004 30 (2): 75-77   ISSN: 2096-5540  CN: 32-1880/R   微透析技术在皮肤科的应用 冯华, 郑家润 中国医学科学院、中国协和医科大学皮肤病研究所, 南京 210042 收稿日期 2003-01-02  修回日期 null  网络版发布日期 null 参考文献  [1] Schnetz E, Fartasch M. Microdialysis for the evaluation of penetration through the human skin barrier-a promising tool for future research?Eur J Pharm Sci, 2001, 12(3):165-174. [2] Stahl M, Bouw R, Jackson A, et al. Human microdialysis. Curr Pharm Biotechnol, 2002, 3(2):165-178. [3] Garrison KE, Pasas SA, Cooper JD, et al. A review of membrane sampling from biological tissues with applications in pharmacokinetics,metabolism and pharmacodynamics. Eur J Pharm Sci, 2002, 17(1-2):1-12. [4] Groth L. Cutaneous microdialysis. Methodology and validation. Acta Derm Venereol Suppl(Stockh), 1996, 197:1-61. [5] Groth L, Jorgensen A, Serup J. Cutaneous microdialysis in the rat:insertion trauma and effect of anaesthesia studied by laser Doppler perfusion imaging and histamine release. Skin Phannacol Appl Skin Physiol, 1998, 11(3):125-132. [6] Borg N, Gotharson E, Benfeldt E, et al. Distribution to the skin of penciclovir after oral famciclovir administration in healthy volunteers:comparison of the suction blister technique and cutaneous microdialysis. Acta Derm Venereol, 1999, 79(4):274-277. [7] Sjogren F, Svensson C, Anderson C. Technical prerequisites for in vivo microdialysis determination of interleukin-6 in human dermis. Br J Dermatol, 2002, 146(3):375-382. [8] Leveque N, Robin S, Makki S,et al. Iron concentrations in human dermis assessed by microdialysis associated with atomic absorption spectrometry. Biol Pharm Bull, 2001, 24(1):10-13. [9] Boschmann M, Murphy FP, Krueger JG. Microdialysis can detect age-related differences in glucose distribution within the dermis and subcutaneous adipose tissue. Dermatology, 2001,202(3):207. [10] Leveque N, Muret P, Mary S, et al. Decrease in skin ascorbic acid concentration with age. Eur J Dermatol, 2002, 12(4):ⅩⅪ-ⅩⅫ. [11] Crandall CG, Shibasaki M, Yen TC. Evidence that the human cutaneous venoarteriolar response is not mediated by adrenergic mechanisms. J Physiol, 2002, 538(Pt 2):599-605. [12] Kellogg DL Jr, Liu Y, Pergola PE. Selected contribution:Gender differences in the endothelin-B receptor contribution to basal cutaneous vascular tone in humans. J Appl Physiol, 2001,91(5):2407. [13] Clough GF, Church MK. Vascular responses in the skin:an accessible model of inflammation. News Physiol Sci, 2002, 17:170-174. [14] Krogstad AL, Lonnroth P, Larson G, et al. Nerve-induced histamine release is of little importance in psoriatic skin. Br J Dermatol, 1998,139(3):403-409. [15] Rhodes LE, Belgi G, Parslew R,et al. Ultraviolet-B-induced erythema is mediated by nitric oxide and prostaglandin E2 in combination. J Invest Dermatol, 2001, 117(4):880-885. [16] Rukwied R, Zeck S, Schmelz M, et al. Sensitivity of human scalp skin to pruritic stimuli investigated by intradermal microdialysis in vivo. J Am Acad Dermatol, 2002, 47(2):245-250. [17] Neisius U, Olsson R, Rukwied R, et al. Prostaglandin E2 induces vasodilation and pruritus, but no protein extravasation in atopic dermatitis and controls. J Am Acad Dermatol, 2002, 47(1):28-32. [18] Kreilgaard M, Kemme MJ, Burggraaf J, et al. Influence of a microemulsion vehicle on cutaneous bioequivalence of a lipophilic model drug assessed by microdialysis and pharmacodynamics. Pharm Res, 2001,18(5):593-599. [19] Kreilgaard M. Dermal pharmacokinetics of microemulsion formulations determined by in vivo microdialysis. Pharm Res, 2001, 18(3):367. [20] Luengo J, Aranguiz T, Sepulveda J, et al. Preliminary pharmacokinetic study of different preparations of acyclovir with beta-cyclodextrin. J Pharm Sci, 2002, 91(12):2593-2598. [21] Legat FJ, Maier A, Dittrich P, et al. Penetration of fosfomycin into inflammatory lesions in patients with cellulitis or diabetic foot syndrome. Antimicrob Agents Chemother, 2003, 47(1):371-374. [22] Nielsen PN, Skov PS, Poulsen LK, et al. Cetirizine inhibits skin reactions but not mediator release in immediate and developing latephase allergic cutaneous reactions. A double-blind, placebo-controlled study. Clin Exp Allergy, 2001,31(9):1378-1384. [23] Petersen LJ, Skov PS. The effect of salmeterol and salbutamol on mediator release and skin responses in immediate and late phase allergic cutaneous reactions. Inflamm Res, 1999, 48(10):527-532. [24] Joukhadar C, Klein N, Mader RM, et al. Penetration of dacarbazine and its active metabolite 5-aminoimidazole-4-carboxamide into cutaneous metastases of human malignant melanoma. Cancer, 2001,92(8):2190-2196. 通讯作者: