国际皮肤性病学杂志    2003 29 (3): 158-160   ISSN: 2096-5540  CN: 32-1880/R   白癜风与一氧化氮及其相关因子 谭雪晶1, 涂彩霞2, 林熙然1 1. 大连医科大学附属第一医院皮肤科, 大连116011; 2. 大连医科大学附属第二医院皮肤科 收稿日期 2002-06-21  修回日期 null  网络版发布日期 null 参考文献  [1] Bicker G. Sources and targets of nitric oxide signalling in insect nervous systems. Cell Tissue Res, 2001,303(2):137-146. [2] Jackson M, Frame F, Weller R, et al. Expression of nitric oxide synthase Ⅲ (eNOS) mRNA by human skin cells:melanocytes but not keratinocytes express eNOS mRNA. Arch Dermatol Res, 1998, 290(6):350-352. [3] Singh VK, Mehrotra S, Narayan P, et al. Modulation of autoimmune diseases by nitric oxide. Immunol Res, 2000, 22(1):1-19. [4] Liaudet L, Soriano FG, Szabo C. Biology of nitric oxide signaling.Crit Care Med, 2000, 28(4 Suppl):N37-52. [5] Rocha IM, Guillo LA. Lipopolysaccharide and cytokines induce nitric oxide synthase and produce nitric oxide in cultured normal human melanocytes. Arch Dermatol Res, 2001, 293 (5):245-248. [6] Brune B, Sandau K, von Knethen A. Apoptotic cell death and nitric oxide:activating and antagonistic transducing pathways. Biochemistry (Mosc), 1998, 63 (7):817-825. [7] Kroncke KD, Brenner HH, Rodriguez ML,et al. Pancreatic islet cells are highly susceptible towards the cytotoxic effects of chemically generated nitric oxide. Biochim Biophys Acta, 1993, 1182(2):221-229. [8] Ivanova K, Le Poole IC, Gerzer R, et al. Effect of nitric oxide on the adhesion of human melanocytes to extracellular matrix components. J Pathol, 1997, 183(4):469-476. [9] Kolb H, Kolb-Bachofen V. Nitric oxide:a pathogenetic factor in autoimmunity. Immunol Today, 1992, 13(5):157-160. [10] Kroncke KD, Fehsel K, Kolb-Bachofen V. Nitric oxide:cytotoxicity versus cytoprotection-how, why, when, and where? Nitric Oxide,1997, 1(2):107-120. [11] Chang RH, Feng MH, Liu WH, et al. Nitric oxide increased intedeukin-4 expression in T lymphocytes. Immunology, 1997, 90 (3):364-369. [12] Niedbala W, Wei XQ, Piedrafita D,et al. Effects of nitric oxide on the induction and differentiation of Th1 cells. Eur J Immunol, 1999, 29(8):2498-2505. [13] Huang FP, Niedbala W, Wei XQ,et al. Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages. Ear J Immunol, 1998, 28(12):4062-4070. [14] Mulligan MS, Hevel JM, Marietta MA, et al. Tissue injury caused by deposition of immune complexes is L-arginine dependent. Proc Natl Acad Sci U S A, 1991, 88(14):6338-6342. [15] Kroemer G, Martinez C. Cytokines and autoimmune disease. Clin Immunol Immunopathol, 1991,61 (3):275-295. [16] Liew FY. Regulation of nitric oxide synthesis in infectious and autoimmune diseases. Immunol Lett, 1994, 43 (1-2):95-98. [17] Morelli JG, Norris DA. Influence of inflammatory mediators and cytokines on human melanocyte function. J Invest Dermatol, 1993, 100(2Suppl):S191-S195. [18] Das L, Datta N, Bandyopadhyay S, et al. Successful therapy of lethal murine visceral leishmaniasis with cystatin involves up-regulation of nitric oxide and a favorable T cell response. J Immunol, 2001, 166(6):4020-4028. [19] Tarrant TK, Silver PB, Wahlsten JL, et al. Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma,nitric oxide, and apoptosis. J Exp Med, 1999, 189(2):219-230. [20] Zidek Z, Lotzova E, Frankova D, et al. Indirect stimulatory effects of murine interleukin-12 on in vitro production of nitric oxide by mouse peritoneal cells. J Interferon Cytokine Res, 1996, 16(5):389-393. [21] Lasarte JJ, Corrales FJ, Casares N, et al. Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a coadministered antigen:the role of nitric oxide. J Immunol, 1999,162(9):5270-5277. [22] Goff WL, Johnson WC, Cluff CW. Babesia bovis immunity. In vitro and in vivo evidence for IL-10 regulation of IFN-gamma and iNOS.Ann N Y Acad Sci, 1998, 849:161-180. [23] Becherel PA, Le Goff L, Ktorza S, et al. Interleukin-10 inhibits IgE-mediated nitric oxide synthase induction and cytokine synthesis in normal human keratinocytes. Eur J Immunol, 1995, 25(10):2992-2995. [24] Mallat Z, Heymes C, Ohan J, et al. Expressior of interleukin-10 in advanced human atherosclerotic plaques:relation to inducible nitric oxide synthase expression and cell death. Arterioscler Thromb Vasc Biol, 1999, 19(3):611-616. [25] Relic B, Guicheux J, Mezin F,et al. Ⅱ-4 and IL-13, but not IL 10, protect human synoviocytes from apoptosis. J Immunol, 2001,166(4):2775-2782. [26] Molina-Holgado E, Vela JM, Arevalo-Martin A, et al. LPS/IFN-gamma cytotoxicity in oligodendroglial cells:role of nitric oxide and protection by the anti-inflammatory cytokine IL-10. Eur J Neurosci. 2001,13(3):493-502. [27] Patton EA, La Flamme AC, Pedras-Vasoncelos JA, et al. Central role for interleukin-4 in regulating nitric oxide-mediated inhibition of Tcell proliferation and gamma interferon production in schistosomiasis.Infect Immun, 2002, 70(1):177-184. 通讯作者: