国际皮肤性病学杂志    2002 28 (6): 353-355   ISSN: 2096-5540  CN: 32-1880/R   瘢痕疙瘩的研究进展 李明, 杨森, 张学军 安徽医科大学皮肤病研究所、第一附属医院皮肤科, 合肥230022 收稿日期 2002-01-11  修回日期 null  网络版发布日期 null 参考文献  [1] Dustan HP. Does keloid pathogenesis hold the key to understanding black/white differences in hypertension severity? Hypertension, 1995,26(6 Pt 1):858-862. [2] Murray JC. Scars and keloids. Dermatol Clin, 1993, 11 (4):697-708. [3] Ghazizadeh M, Miyata N, Sasaki Y, et al. Silver-stained nucleolar organizer regions in hypertrophic and keloid scars. Am J Dermatopathol,1997, 19(5):468-472. [4] Alaish SM, Yager DR, Diegelmann RF, et al. Hyaluronic acid metabolism in keloid fibroblasts. J Pediatr Surg, 1995, 30(7):949-952. [5] Marneros AG, Norris JE, Olsen BR, et al. Clinical genetics of familial keloids. Arch Dermatol, 2001, 137 (11):1429-1434. [6] Saed GM, Ladin D, Olson J, et al. Analysis of p53 gene mutations in keloids using polymerase chain reaction-based single-strand conformational polymorphism and DNA sequencing. Arch Dennatol, 1998, 134(8):963-967. [7] Nirodi CS, Devalaraja R, Nanney LB, et al. Chemokine and chemokine receptor expression in keloid and normal fibroblasts. Wound Repair Regen, 2000, 8(5):371-382. [8] Peltonen J, Hsiao LL, Jaakkola S, et al. Activation of collagen gene expression in keloids:co-localization of type Ⅰ and Ⅵ collagen and transforming growth factor-beta 1 mRNA. J Invest Dermatol, 1991,97(2):240-248. [9] Igarashi A, Nashiro K, Kikuchi K, et al. Connective tissue growth factor gene expression in tissue sections from localized scleroderma,keloid, and other fibrotic skin disorders. J Invest Dermatol, 1996,106(4):729-733. [10] Xue H, McCauley RL, Zhang W. Elevated interleukin-6 expression in keloid fibroblasts. J Surg Res, 2000, 89(1):74-77. [11] Oriente A, Fedarko NS, Pacocha SE, et al. Interleukin-13 modulates collagen homeostasis in human skin and keloid fibroblasts. J Pharmacol Exp Ther, 2000, 292 (3):988-994. [12] Luo S, Benathan M, Raffoul W, et al. Abnormal balance between proliferation and apoptotic cell death in fibroblasts derived from keloid lesions. Plast Reconstr Surg, 2001, 107(1):87-96. [13] Messadi DV, Le A, Berg S, et al. Expression of apoptosis-associated genes by human dermal scar fibroblasts. Wound Repair Regen, 1999,7(6):511-517. [14] Kossi J, Peltonen J, Uotila P, et al. Differential effects of hexoses and sucrose, and platelet-derived growth factor isoforms on cyclooxygenase1 and-2 mRNA expression in keloid, hypertrophic scar and granulation tissue fibroblasts. Arch Dermatol Res, 2001, 293 (3):126-132. [15] Higgins PJ, Slack JK, Diegelmann RF, et al. Differential regulation of PAI-1 gene expression in human fibroblasts predisposed to a fibrotic phenotype. Exp Cell Res, 1999, 248(2):634-642. [16] Stucker FJ, Shaw GY. An approach to management of keloids. Arch Otolaryngol Head Neck Surg, 1992, 118 (1):63-67. [17] Nemeth AJ. Keloids and hypertrophic scars. J Dermatol Surg Oncol,1993, 19(8):738-746. [18] Chowdri NA, Masarat M, Mattoo A, et al. Keloids and hypertrophic scars:results with intraoperative and serial postoperative corticosteroid injection therapy. Aust N Z J Surg, 1999, 69(9):655-659. [19] Kauh YC, Rouda S, Mondragon G,et al. Major suppression of pro-alpha1 (I) type Ⅰ collagen gene expression in the dermis after keloid excision and immediate intrawound injection of triameinolone acetonide. J Am Acad Dermatol, 1997, 37(4):586-589. [20] LeeY, Minn KW, Baek RM, et al. A new surgical treatment of keloid:keloid core excision. Ann Plast Surg, 2001,46(2):135-140. [21] Norris JE. The effect of carbon dioxide laser surgery on the recurrence of keloids. Plast Reconstr Surg, 1991,87(1):44-49; discussion 50-53. [22] Layton AM, Yip J, Cunliffe WJ. A comparison of intralesional triamcinolone and cryosurgery in the treatment of acne keloids. Br J Dermatol,1994,130(4):498-501. [23] Connell PG, Harland CC. Treatment of keloid scars with pulsed dye laser and intralesional steroid. J Cutan Laser Ther, 2000,2 (3):147-150. [24] Espana A, Solano T, Quintanilla E. Bleomycin in the treatment of keloids and hypertrophic scars by multiple needle punctures. Dermatol Surg, 2001, 27(1):23-27. [25] Berman B, Flores F. The treatment of hypertrophic scars and keloids.Eur J Dermatol,1998,8(8):591-595. 通讯作者: