国际皮肤性病学杂志    2002 28 (4): 233-236   ISSN: 2096-5540  CN: 32-1880/R  

端粒酶在皮肤病学中的研究进展
宋秀祖, 毕志刚
南京医科大学附属第一医院皮肤科 210029
收稿日期 2001-12-18  修回日期 null  网络版发布日期 null
参考文献  [1] Blackburn EH.Structure and function of telomeres.Nature,1991,350(6319):569-573.
[2] Shore D.Telomerase and telomere-binding proteins:controlling the endgame.Trends Biochem Sci,1997,22(7):233-235.
[3] Morin GB.The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats.Cell,1989,59(3):521-529.
[4] Wu A,Ichihashi M,Ueda M.Correlation of the expression of human telomerase subunits with telomerase activity in normal skin and skin tumors.Cancer,1999,86(10):2038-2044.
[5] Harley CB,Futcher AB,Greider CW.Telomeres shorten during ageing of human fibroblasts.Nature,1990,345(6274):458-460.
[6] Ouellette MM,Liao M,Herbert BS,et al.Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase.J Biol Chem,2000,275(14):10072-10076.
[7] Harle-Bachor C,Boukamp P.Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes.Proc Natl Acad Sci U S A,1996,93(13):6476-6481.
[8] Yasumoto S,Kunimura C,Kikuchi K,et al.Telomerase activity in normal human epithelial cells.Oncogene,1996,13(2):433-439.
[9] Ramirez RD,Wright WE,Shay JW,et al.Telomemse activity concentrates in the mitotically active segments of human hair follicles.J Invest Dermatol,1997,108(1):113-117.
[10] Bednarek A,Budunova I,Slaga TJ,et al.Increased telomerase activity in mouse skin premalignant progression.Cancer Res,1995,55(20):4566-4569.
[11] Blasco MA,Rizen M,Greider CW,et al.Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis.Nat G,enet,1996,12(2):200-204.
[12] Balasubmmanian S,Kim KH,Ahmad N,et al.Activation of telomerase and its association with Gl-phase of the cell cycle during UVB-induced skin tumorigenesis in SKH-1 hairless mouse.Oncogene,1999,18(6):1297-1302.
[13] Ueda M,Ouhtit A,Bito T,et al.Evidence for UV-associated activation of telomerase in human skin.Cancer Res,1997,57(3):370-374.
[14] Glaessl A,Bosserhoff AK,Buettner R,et al.Increase in telomerase activity during progression of melanocytic cells from melanocytic naevi to malignant melanomas.Arch Dermatol Res,1999,291(2-3):81-87.
[15] Tosi P,Miracco C,Santopietro R,et al.Possible diagnostic role of telomerase activity evaluation in the differential diagnosis between spitz naevi and cutaneous malignant melanoma.Br J Dermatol,2000,142(5):1060-1061.
[16] Villa R,Porta CD,Folini M,et al.Possible regulation of telomerase activity by transcription and alternative splicing of telomerase reverse transcriptase in human melanoma.J Invest Dermatol,2001,116(6):867-873.
[17] Stoppler H,Stoppler MC,Kisiela M,et al.Telomerase activity of Merkel cell carcinomas and Merkel cell carcinoma-derived cell cultures.Arch Dermatol Res,2001,293(8):397-406.
[18] Mitchell JR,Wood E,Collins K.A telomerase component is defective in the human disease dyskeratosis congenita.Nature,1999,402(6761):551-555.
[19] Vulliamy T,Marrone A,Goldman F,et al.The RNA component of telomerase is mutated in autosomal dominant dyskeertosis congenita.Nature,2001,413(6854):432-435.
[20] Parris CN,Jezzard S,Silver A,et al.Telomerase activity in melanoma and non-melanoma skin cancer.Br J Cancer,1999,79(1):47-53.
[21] Jang HS,Oh CK,Jo JH,et al.Detection of telomerase activity in psoriasis lesional skin and correlation with Ki-67 expression and suppression by retinoic acid.J Korean Med Sci,2001,16(5):623-629.
[22] Zhao P,Li X,Yang Z,et al.Telomerase activity in radiation-induced chronic human skin ulcers.J Environ Pathol Toxicol Oncol,1999,18(1):17-19.
[23] Rea MA,Phillips MA,Degraffenried LA,et al.Modulation of human epidermal cell response to 2,3,7,8-tetrachlorodibenzo-p-dioxin by epidermal growth factor.Carcinogenesis,1998,19(3):479-483.
[24] Franzese O,Comandini A,Cannavo E,et al.Effect of prostaglandin A1 on proliferation and telomerase activity of human melanoma cells in vitro.Melanoma Res,1998,8(4):323-328.
[25] Kallassy M,Martel N,Damour O,et al.Growth arrest of immortalized human keratinocytes and suppression of telomerase activity by p21WAF1 gene expression.Mol Carcinog,1998,21(1):26-36.
[26] Bickenbach JR,Vormwald-Dogan V,Bachor C,et al.Telomerase is not an epidermal stem cell marker and is downregulated by calcium.J Invest Dermatol,1998,111(6):1045-1052.

通讯作者: