国际皮肤性病学杂志    2002 28 (3): 166-169   ISSN: 2096-5540  CN: 32-1880/R   CXCR3及其配体与皮肤病 刘伦飞, 郑敏 浙江大学医学院附属第二医院皮肤科 杭州 310009 收稿日期 2001-08-29  修回日期 null  网络版发布日期 null 参考文献  [1] Loetscher M,Gerber B,Loetscher P,et al.Chemokine receptor specific for IP10 and mig:structure,function,and expression in activated T-lymphocytes.J Exp Med,1996,184(3):963-969. [2] Loetscher M,Loetscher P,Brass N,et al.Lymphocyte-specific chemokinereceptor CXCR3:regulation,chemokine binding and gene localization.Eur J Immtmol,1998,28(11):3696-3705. [3] Saleedo R,Resan JH,Halverson D,et al.Differential expression and re-sponsiveness of chemokine receptors(CXCR1-3) by hmann microvascular endothelial cells and umbilical vein endothelial cells.FASEB J,2000,14(13):2055-2064. [4] Farter JM.HuMig:a new human member of the ehemokine family of cytokines.Biochem Biophys Res Commtm,1993,192(1):223-230. [5] Liao F,Rabin RL,Yannelli JR,et al.Human Mig chemokine:biochemical and functional characterization.J Exp Med,1995,182(5):1301-1314. [6] Luster AD,Ravetch JV.Biochemical characterization of a gamma interfer-on-inducible cytokine(IP-10).J Exp Med,1987,166(4):1084-1097. [7] Cole KE,Strick CA,Paradis TJ,et al.Interferon-inducible T cell alpha chemoattractant(I-TAC):a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CX-CR3.J Exp Med,1998,187(12):2009-2021. [8] Tensen CP,Flier J,Van Der Raaij-Helmer EM,et al.Human IP-9:A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/ Mig receptor(CXCR3).J Invest Dermatol,1999,112(5):716-722. [9] Cox MA,Jenh CH,Gonsiorek W,et al.Human interferon-inducible 10kDa protein and human interferon-inducible T cell alpha chemeattractant are allotopic tigands for human CXCR3:differential binding to receptor states.Mol Pharmacol,2001,59(4):707-715. [10] Belporio JA,Keane MP,Arenberg DA,et al.CXC chemokines in anglo-genesis.J Leukoc Biol,2000,68(1):1-8. [11] Romagnani P,Annunziato F,Lasagni L,et al.Cell cycle-dependent ex-pression of CXC chemokine receptor 3 by endothelial cells mediates anglostatic activity.J Clin Invest,2001,107(1):53-63. [12] Angiolillo AL,Sgadafi C,Taub DD,et al.Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo.J Exp Med,1995,182(1):155-162 [13] Bonacchi A,Romagnani P,Romanelli RG,et al.Signal transduction by the chemokine receptor CXCR3:activation of Ras/ERK,Src,and phos-phatidylinositol 3-kinase/Akt controls cell migration and proliferation in human vascular pericytes.J Biol Chem,2001,276(13):9945-9954. [14] Flier J,Boorsma DM,Bruynzeel DP,et al.The CXCR3 activating chemokines IP-10,Mig,and IP-9 are expressed in allergic hat not in irritant patch test reactions.J Invest Dermatol,1999,113(4):574-578. [15] Smolhr BR,Luster AD,Krane JF,et al.Fixed drug eruptions:evidence for a cytokine-mediated process.J Cutan Pathol,1991,18(1):13-19. [16] Giustizieri ML,Mascia F,Frezzolini A,et al.Keratinocytes from patients with atepie dermatitis and psoriasis show a distinct ehemokine production profde in response to T cell-derived cytokines.J Allergy Clin Immunol,2001,107(5):871-877. [17] Gottlieb AB,Luster AID,Posnett DN,et al.Detection of a gamma inter-feron-induced protein IP-10 in psoriatic plaques.J Exp Med,1988,168(3):941-948. [18] Rottman JB,Smith TL,Ganley KG,et al.Potential role of the chemokine receptors CXCR3,CCR4,and the integrin alphaEhata7 in the pathogene-sis of psoriasis vulgaris.Lab Invest,2001,81(3):335-347. [19] Goebeler M,Toksoy A,Spandan U,et al.The C-X-C chemokine Mig is highly expressed in the papillae of psoriatic lesions.J Pathol,1998,184(1):89-95. [20] Sgadari C,Farhar JM,AngioliUo AL,et al.Mig,the monokine induced by interferon-gamma,promotes tumor necrosis in vivo.Blood,1997,89(8):2635-2643. [21] Kunz M,Toksoy A,Gcebeler M,et al.Strong expression of the lymphoat-tractant C-X-C ehemokine Mig is associated with heavy infiltration of T cells in human malignant melanoma.Pathol,1999,189(4):552-558. [22] Sarris AH,Daliani D,Ulmer R,et al.Interferon-inducible protein 10 as a possible factor in the pathogenesis of cutaneous T-celi lymphomas.Clin Cancer Res,1997,3(2):169-177. [23] Tensen CP,Vermcer MH,van der Stoop PM,et al.Epidermal interferon-gamma inducible protein-10(IP-10) and monokine induced by gamma-in-terferon(Mig) but not IL-8 mRNA expression is associated with epider-metrepism in cutaneous T cell lymphomas.J Invest Dermatol,1998,111(2):222-226. [24] Lu D,Duvic M,Medeiros LJ,et al.The T-cell chemokine receptor CX-CR3 is expressed highly in low-grade mycosis fungoides.Am J Clin Pathol,001,115(3):413-421. [25] Patel DD,Zachariah JP,Whiehard LP.CXCR3 and CCR5 ligands in rheumatoid arthritis synovium.Clin Immunol,2001,98(1):39-45. [26] Narumi S,Takenchi T,Kohayashi Y,et al.Serum levels of ifnindueible PROTEIN-10 relating to the activity of systemic lupus erythematosus.Cytokine,2000,12(10):1561-1565. 通讯作者: