国际皮肤性病学杂志    2001 27 (5): 296-299   ISSN: 2096-5540  CN: 32-1880/R   尖锐湿疣的免疫学发病机制 郭红卫综述, 吴志华审校, 钱起丰审校 广东医学院皮肤性病研究所 收稿日期 null  修回日期 null  网络版发布日期 null 参考文献  [1] Persson G, Andersson K, Krantz I. Symptomatic genital papillomavirus infection in a commumity. Incidence and clinical picture. Acta Obstet Gynecol Scand, 1996,75(3):287-290. [2] Liu Y, Linsley PS. Costimulation of T cell growth. Curr Opin Immunol, 1992,4(3):265-270. [3] Tendler Y, Schwartz Y, Reshef R, et al. Immunohistochemical detection of p53 protein expression in HPV-induced condyloma acuminatum. Acta Derm Venereol, 1995,75(3):177-179. [4] Arany I, Tyring SK. Status of local celular immunity in interferon-responsive and nonresponsive human papillomavirus-associated lessions. Sex Transm Dis, 1996,23(6):475480. [5] Arany I, Rady P, Zyring SK, et al. Effect of IFN therapy on HPV copy number in patients with condyloma acuminatum. Am J Med Sci, 1995,310(1):14-18. [6] Arany I, Nagamam K, Tyring SK. Interferon resistance is independent from copy numbers in benign HPV-induced lesions. Anticancer Res,1995,15(3):1003-1006. [7] Arany I, Goel A, Tyring SK. Interferon response depends on viral transcription in HPV-containing lessions. Anticancer Res, 1995, 15(6B):2865-2869. [8] Kubin M, Chow JM, Trinchieri G. Differential regulation of IL-12, TNFα and IL-Iβ production in human myeloid leukemia cell lines and peripheral blood mononuclear cells. Blood, 1994,83(7):1847-1855. [9] Wrenshall LE, Platt JL. Regulation of T cell homeostasis by heparan sulfate-bound IL-2. J Immunol, 1999,163(7):3793-3800. [10] Cardamakis E, Kotoulas IG, Relakis K. Comparative study of systemic interferon-alfa-2a plus isotretinoin versus isotretinoin in the treatment of recurrent condyloma acuminatum in men. Urology, 1995,45(5):857-860. [11] Carlson NG, Wieggel WA, Chen J, et al. Inflammatory cytokines IL-1α,IL-Iβ, IL-6 and TNF-α impart neuroprotection to an excitotoxin through distinct pathways. J Immunol, 1999,163(7):3963-3968. [12] Cohen MC, Cohen S. Cytokine function:a study in biologic diversity.Am J Clin Pathol, 1996, 105(5):589-598. [13] Wynn TA, Morawetz R, Scharton-kersten T, et al. Analysis of granuloma formation in double cytokine-deficient mice reveals a central role for IL-10 in polarizing both T helper cell 1-and T helper cell 2-type cytokine respones in vivo. J Immunol, 1997, 159(10):5014-5023. [14] Lasek W, Golab J, Maslinski W, et al. Subtherapeutic doses of IL-15 augment the antitumor effect of IL-12 in a B16F10 melanoma model in mice. Eur Cytokine Netw. 1999,10(3):345-356. [15] Wu Q, Wang Y, Wang J, et al. The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissues. J Exp Med,1999,190(5):629-638. [16] Tsujino S, Miyazaki T, Kawahara A, et al. Critical role of the membraneproximal, proline-rich motif of the IL-2 receptor gammac chain in the Jak3-independent signal transduction. Genes Cells, 1999,4(6):363-373. [17] Abbas AK, Murphy KM, Sher A, et al. Functional diversity of helper T lymphocytes. Nature, 1996,383(6603):787-793. [18] Gonrad CT, Ernst NR, Dummer W,et al. Differential expression of TGF-β,and IL-10 in progression and regressing areas of primary melanoma. J Exp Clin Cancer Res, 1999, 18(2):225-232. 通讯作者: