国际皮肤性病学杂志    2001 27 (5): 288-290   ISSN: 2096-5540  CN: 32-1880/R   恶性黑素瘤核酸疫苗免疫影响因素及对策 李春英综述, 高天文审校 第四军医大学西京医院皮肤科 收稿日期 null  修回日期 null  网络版发布日期 null 参考文献  [1] Wolff JA, Malone RW, Williams P, et al. Direct gene transfer into mouse muscle in vivo. Science, 1990,247(4949 Pt 1).1465-1468. [2] Reimann J, Kaufmann SH. Altemative antigen processing pathways in anti-infective immunity. Curr Opin Immunol, 1997,9(4):462-469. [3] Stenger S, Modlin RL. Cytoxic T cell responses to intracellular pathogens.Curr Opin Immunol, 1998,10(4):471-477. [4] Reis e Sousa C, Sher A, Kaye P. The role of dendritic cells in the induction and regulation of immunity to microbial infection. Curr Opin Immunol,1999, 11(4):392-399. [5] Doe B, Selby M, Barnett S, et al. Introduction of cytotoxic T lymphucytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow derived cells. Proc Natl Acad Sci USA, 1996, 93(16):8578-8583. [6] Park JH, Kim CJ, Lee JH, et gl. Effective immunotherapy of cancer by DNA vaccination. Mol Cells, 1999,9(4):384-391. [7] Ribas A, Butterfield LH, McBride WH, et al. Genetic immunization for the melanoma antigen MART-1/Melan-A using recombinant adenovirustransduced murine dendritic cells. Cancer Res, 1997,57(14):2865-2869. [8] Zhou WZ, Kaneda Y, Huang S, et al. Protective immunization against melanoma by gp100 DNA-HVJ-liposome vaccine. Gene Ther, 1999, 6(10):1768-1773. [9] Bronte V, Apolloni E, Ronca R, et al. Genetic vaccination with "self" tyrosinase-related protein 2 causes melanoma eradication but not vitiligo.Cancer Res, 2000,60(2):253-258. [10] Krieg AM, Yi Ak, Matson S, et al. CpG, motifs in bacterial DNA trigger direct B-cell activation. Nature, 1995,374(6522):546-549. [11] Janik JE, Miller LL, Kopp WC, et al. Treatment with tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor increases epidermal Langerhans' cell numbers in cancer patients. Clin Immunol,1999, 93(3):209-221. [12] Tuting T, Gambotto A, DeLco A,et al. Induction of tumor antigen-specific immunity using plasmid DNA immunization in mice. Cancer Gene Ther,1999,6(1):73-80. [13] Nawrath M, Heinrich J, Strack B, et al. A DNA vaccine against malignant melanoma coexpressing antigen and cytokine. Adv Exp Med Biol,1998,451:305-310. [14] Xiang R, Lode HN, Chao TH, et al. An autologous oral DNA vaccine protects against murine melanoma. Proc Natl Acad Sci USA, 2000, 97(10):5492-5497. [15] Hawkins WG, Gold JS, Dyall R, et al. Immunization with DNA coding for gp100 results in CD4 T-cell independent antitumor immunity. Surgery,2000, 128(2):273-280. [16] Steitz J, Bruck J, Steinbrink K, et al. Genetic immunization of mice with human tyrosinase-related protein 2:implications for the immunotherapy of melanoma. Int J Cancer, 2000,86(1):89-94. [17] Novakovic S, Ihan A, Jezersek B. Effectivenness of a simply designed tumor vaccine in prevention of malignant melanoma development. Jpn J Cancer Res, 1999,90(10):1130-1138. 通讯作者: