国际皮肤性病学杂志    2001 27 (5): 274-276   ISSN: 2096-5540  CN: 32-1880/R  

皮肤病的Th1/Th2模式
阎衡综述, 叶庆佾审校, 郝飞审校
第三军医大学西南医院皮肤科
收稿日期 null  修回日期 null  网络版发布日期 null
参考文献  [1] Singh VK, Mehrotra S, Agarwal SS. The paradigm of Th1 and Th2 cytokines:its relevance to autoimmunity and allergy. Immunol Res. 1999,20(2):147-161.
[2] Mozzanica N, Cattaneo A, Trabattoni D, et al. Production of type-1 and type-2 cytokines by peripheral blood mononuclear cells of psoriatic patients. Immunology, 1995, 86(3):422-426.
[3] Austin LM, Ozawa M, Kikuchi T, et al. The majority of epidermal T cells in psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TCL(cytotoxic T lymphocyte) and TH1 effector populations:a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J Invest Dermatol, 1999, 113(5):752-759.
[4] Romani L. Immunity to Candida albicans:Th1. Th2 cells and beyond.Curr Opin Microbiol, 1999, 2(4):363-367.
[5] Lavigne LM, Schopf LR, Chung CL, et al. The role of reconbinant murine IL-12 and IFN-gamma in the pathogenesis of a murine systemic Candida albicans infection. J Immunol, 1998, 160(1):284-292.
[6] Wong CK, Ho CY, Li EK, et al. Elevation of proinflammatory cytokine(IL-18, IL-17, IL-12) and Th2 cytokine(IL-4) coucentrations in patients with systemic lupus erythematosus. Lupus, 2000, 9(8):589-593.
[7] Akahoshi M, Nakashima H, Tanaka Y, et al. Thl/Th2 balance of peripheral T helper cells in systemic lupus erythematosus. Arthritis Rheum,1999, 42(8):1644-1648.
[8] Teraki Y, Hotta T, Shiohara T. Increased circulating skin-homing cutaneous lymphocyte-associated antigen(CLA) + type 2 cytokine-producing cells, and decreased CLA + type I cytokine-producing cells in atopic dermatitis. Br J Dermatol, 2000, 143(2):373-378.
[9] Rowe A, Bunker CB. Interleukin-4 and the interleukin-4 receptor in allergic contact dermatitis. Contact Dermatitis, 1998, 38(1):36-39.
[10] Voiculescu C, Avramescu C, Radu E, et al. Current laboratory assays and in vitro intracellular Th1 and Th2 cytokine synthesis in monitoring antiretroviral therapy of pediatric HIV infection. FEMS Immunol Med Microbiol, 2000, 27(1):67-71.
[11] Ong CJ, Ip S, Teh SJ, et al. A role for T helper 2 cells in mediating skin fibrosis in tight-skin mice. Cell I mmunol, 1999, 196(1):60-68.
[12] Hertl M, Riechers R.Analysis of the T cells that are potentially involved in autoantibody production in pemphigus vulgaris. J Dermatol, 1999, 26(11):748-752.
[13] Murray HW, Haripraxhad J, Coffman RL. Behavior of visceral Leishania donovani in an experimentally induced T helper cell 2(Th2)-associated response model. J Exp Med, 1997, 185(5):867-874.
[14] Falcone M, Rajan AJ, Bloom BR, et al. A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BAB/c mice. J Immunol,1998, 160(10):4822-4830.
[15] Hong K, Chu A, Ludviksson BR, et al. IL-12, independently of IFNgamma, plays a crucial role in the pathogenesis of a murine psoriasis-like skin disorder. J Immunol, 1999, 162(12):7480-7491.
[16] Joosten LA, Lubberts E, Helsen MM, et al. Dual role of IL-12 in early and late stages of murine collagen type Ⅱ arthritis. J Immunol, 1997, 159(8):4094-4102.
[17] Vandenborre K, Van Gool SW, Kasran A, et al. Interaction of CTLA4(CD152) with CD80 or CD86 inhibits human T-cell uctivation. Immunology, 1999, 98(3):413421.
[18] Abrams JR, Lebwohl MG, Guzzo CA, et al. CTLA4-Ig mediated blockade of T cell costimutation on patients with psoriasis vulgaris. J Clin Invest,1999, 103(9):1243-1252.
[19] Finck BK, Linsley PS, Wofsy D. Treatment of murine lupus with CTLA4-Ig. Science, 1994, 265(5176):1225-1227.
[20] Kusakabe K, Xin KQ, Katoh H, et al. The timing of GM-CSF expression plasmid administration infleuences the Th1/Th2 response induced by an HIV-1-specific DNA vaccine. J Immunol, 2000, 164(6):3102-3111.
[21] Xiao BG, Link H. Mucosal tolerance:a two-edged sword to prevent and treat autoimmune diseases. Clin Immunol Immunopathol, 1997, 85(2):119-128.

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