国际皮肤性病学杂志    2001 27 (3): 138-140   ISSN: 2096-5540  CN: 32-1880/R   天疱疮发病机理的某些研究进展 周淑华综述1, 林麟审校2, 叶顺章审校2 1. 中国医学科学院皮肤病研究所; 2. 中国协和医科大学皮肤病研究所 收稿日期 null  修回日期 null  网络版发布日期 null 参考文献  [1] Amagai M,Koch PJ,Nishikawa T,et al.Pemphigus vulgaris antigen(desmoglein-3) is localized in the lower epidermis,the site of blister formation in patients.J Invest Dermatol,1996,106(2):351-355. [2] Wilson CL,Wojnarowska F,Dean D,et at.IgG subclasses in pemphigus in Indian and UK populations.Clin Exp Dermatol,1993,18(3):226-230. [3] Amagai M,Klaus-Kovtun V,Stanley JR.Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris,a disease of cell adhesion.Cell,1991,67(5):867-877. [4] Ishii K,Amagai M,Hall RP,et al.Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins.J Immunol,1997,159(4):2010-2017. [5] Dmochowski M,Hashimoto T,Chidgey MA,et al.Demonstration of antibodies to bovine desmocollin isoforms in certain pemphigus sera.BrJ Dermatol,1995,133(4):519-525. [6] Amagai M,Tsunoda K,Zillikens D,et al.The clinical phenotype of pemphigus is defined by the anti-desmoglein autoantibody profile.J Am Acad Dermatol,1999,40(2 Pt 1):167-170. [7] Ahmed AR,Wagner R,Khatri K,et al.Major histocompatibility complex haplotypes and class Ⅱ genes in non-Jewish patients with pemphigus vulgaris.Proc Natl Acad Sci USA,1991,88(11):5056-5960. [8] Matzner Y,Erlich HA,Brautbar C,et al.Identical HLA class Ⅱ alleles predispose to drug-triggered and idiopathic pemphigus vulgaris.Acta Derm Venereol,1995,75(1):12-14. [9] Miyagawa S,Higashimine I,Iida T,et al.HLA-DRB1 * 04 and DRB1 * 14 alleles are associated with susceptibility to pemphigus among Japanese.J Invest Dermatol,1997,109(5):615-618. [10] Memar OM,Rady PL,Goldblum RM,et al.Human herpesvirus 8 DNA sequences in blistering skin from patients with pemphigus.Arch Dermatol,1997,133(10):1247-1251. [11] Zillikens D,Ambach A,Zentner A,et al.Evidence for cell-mediated immune mechanisms in the pathology of pemphigus.Br JDermatol,1993,128(6):636-643. [12] Mashkilleyson N,Konttinen YT,Visa K.Local involvement of antigen-presenting cells and activated T cells in perilesional and clinically uninvolved skin in pemphigus vulgaris.Acta Derm Venereol,1989,69(5):424-428. [13] Nestor MS,Cochran AJ,Ahmed AR.Mononuclear cell infiltrates in bullous disease.J Invest Dermatol,1987,88(2):172-175. [14] Lin MS,Swartz SJ,Lopez A,et al.Characterization of desmoglein-1 epitopes recognized by T cells from patients with fogo selvagem.J Invest Dermatol,1997,108(4):544. [15] Lin MS,Swartz SJ,Lopez A,et al.Development and characterization of desmoglein-3 specific T cells from patients with pemphigus vulgaris.J Clin Invest,1997,99(1):31-34. [16] Hertl M,Amagai M,Sundaram H,et al.Recognition of desmoglein 3 by autoreactive T cells in pemphigus vulgaris patients and normals.J Invest Dermatol,1998,110(1):62-66. [17] D'Auria L,Bonifati C,Mussi A,et al.Cytokines in the sera of patients with pemphigus vulgaris:interleukin-6 and trmour necrosis factor-alpha levels are significantly increased as compared to healthy subjects and correlate with disease activity.Eur Cytokine Netw,1997,8(4):383-387. [18] Ujihara M,Hamanaka S,Matsuda S,et al.Pemphigus vulgaris associated with autoimmune hemolytic anemia and elevated TNFα.J Dermatol,1994,21(1):56-58. [19] Feliciani C,Toto P,Amerio P,et al.In vitro and in vivo expression of interleukin-1α and tumor necrosis factor-α mRNA in pemphigus vulgaris:interleukin-1α and tumor necrosis factor-αare involved in acantholysis.J Invest Dermatol,2000,114(1):71-77. [20] Rico MJ,Benning C,Weingart ES,et al.Characterization of skin cytokines in bullous pemphigoid and pemphigus vulgaris.Br J Dermatol,1999:140(6):1079-1086. 通讯作者: