国际皮肤性病学杂志    0  (): 364-366   ISSN: 2096-5540  CN: 32-1880/R   银屑病易感基因最新研究进展 范星, 张学军, 杨森 安徽医科大学皮肤病研究所、第一附属医院皮肤科 合肥 230022 收稿日期 2005-03-02  修回日期 null  网络版发布日期 null 参考文献  [1] Orru S, Giuressi E, Carcassi C, et al. Mapping of the major psoriasis-susceptibility locus (PSORS1) in a 70-Kb interval around the corneodesmosin gene (CDSN). Am J Hum Genet, 2005, 76:164-171. [2] Speckman RA, Wright Daw JA, Helms C, et al. Novel immunoglobulin superfamily gene cluster, mapping to a region of human chromosome 17q25, linked to psoriasis susceptibility. Hum Genet, 2003, 112:34-41. [3] Capon F, Semprini S, Chimenti S, et al. Fine mapping of the PSORS4 psoriasis susceptibility region on chromosome 1q21. J Invest Dermatol, 2001, 116:728-730. [4] Capon F, Allen MH, Ameen M, et al. A synonymous SNP of the comeodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups. Hum Mol Genet, 2004, 13:2361-2368. [5] Elomaa O, Majuri I, Suomela S, et al. Transgenic mouse models support HCR as an effector gene in the PSORS1 locus. Hum MolGenet, 2004, 13:1551-1561. [6] Holm SJ, Carlen LM, Mallbris L, et al. Polymorphisms in the SEEK1 and SPR1 genes on 6p21.3 associate with psoriasis in the Swedish population. Exp Dermatol, 2003, 12:435-444. [7] Foerster J, Nolte I, Junge J, et al. Haplotype sharing analysis identifies a retroviral dUTPase as candidate susceptibility gene for psoriasis. J Invest Dermatol, 2005, 124:99-102. [8] Helms C, Cao L, Krueger JG, et al. A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis. Nat Genet, 2003, 35:349-356. [9] Capon F, Helms C, Veal CD, et al. Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis. J Med Genet, 2004, 41:459-460. [10] Sagoo GS, Tazi-Ahnini R, Barker JW, et al. Meta-analysis of genome-wide studies of psoriasis susceptibility reveals linkage to chromosomes 6p21 and 4q28-q31 in Caucasian and Chinese Hans popul ation. J Invest Dermatol, 2004, 122:1401-1405. [11] Villadsen LS, Schuurman J, Beurskens F, et al. Resolution of psori asis upon blockade of IL-15 biological activity in a xenograft mouse model. J Clin Invest, 2003, 112:1571-1580. [12] Baker BS, Ovigne JM, Powles AV, et al. Normal keratinocytes ex press Toll-like receptors (TLRs) 1, 2 and 5:modulation of TLR expression in chronic plaque psoriasis. Br J Dermatol, 2003, 148:670-679. [13] Young HS, Summers AM, Bhushan M, et al. Single-nucleotide poly morphisms of vascular endothelial growth factor in psoriasis of early onset. J Invest Dermatol, 2004, 122:209-215. [14] Foerster J, Nolte I, Schweiger S, et al. Evaluation of the IRF-2 gene as a candidate for PSORS3.J Invest Dermatol, 2004, 122:61-64. [15] Parkinson J, Charon C, Baker BS, et al. Variation at the IRF2 gene and susceptibility to psoriasis in chromosome 4q-linked families. J Invest Dermatol, 2004, 122:640-643. [16] Giardina E, Capon F, De Rosa MC, et al. Characterization of theloricrin (LOR) gene as a positional candidate for the PSORS4 psoriasis susceptibility locus. Ann Hum Genet, 2004, 68:639-645. [17] Samuelsson L, Stiller C, Friberg C, et al. Association analysis of cystatin A and zinc finger protein 148, two genes located at the psoriasis susceptibility locus PSORS5. J Invest Dermatol, 2004, 122:1399-1400. [18] Donn RP, Plant D, Jury F, et al. Macrophage migration inhibitory factor gene polymorphism is associated with psoriasis. J Invest Dermatol, 2004, 123:484-487. [19] Luszczek W, Manczak M, Cislo M, et al. Gene for the activatingnatural killer cell receptor, KIR2DS1, is associated with susceptibi lity to psoriasis vulgaris. Hum Immunol, 2004, 65:758-766. [20] Rahman P, Bartlett S, Siannis F, et al. CARD15:a pleiotropic autoimmune gene that confers susceptibility to psoriatic arthritis. Am J Hum Genet, 2003, 73:677-681. [21] Giardina E, Novelli G, Costanzo A, et al. Psoriatic arthritis and CARD15 gene polymorphisms:no evidence for association in theIalian population. J Invest Dermatol, 2004, 122:1106-1107. [22] Reich K, Mossner R, Konig IR, et al. Promoter polymorphisms of the genes encoding tumor necrosis factor-alpha and interleukin1beta are associated with different subtypes of psoriasis characteri zed by early and late disease onset. J Invest Dermatol, 2002, 118:155-163. [23] Hensen P, Asadullah K, Windemuth C, et al. Interleukin-10 promoter polymorphism IL10.G and familial early onset psoriasis. Br J Dermatol, 2003, 149:381-385. [24] Kingo K, Koks S, Nikopensius T, et al. Polymorphisms in the interleukin-20 gene:relationships to plaque-type psoriasis. Genes Immun, 2004, 5:117-121. [25] Koks S, Kingo K, Ratsep R, et al. Combined haplotype analysis of the interleukin-19 and-20 genes:relationship to plaque-type psoriasis. Genes Immun, 2004, 5:662-667. 通讯作者: