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Treatment of SLE is versatile��B-lymphocyte-targeted therapy is a new clinical approach which has not been generally applied in China. International studies have proved it to be highly effective, safe and tolerable. So, it shows a fine application prospect and is expected to offer a new treatment approach to patients with SLE��especially to those resistant to conventional therapy and those suffering from serious adverse side effects. The true efficacy and long-term side effects of this approach remain to be further evaluated via large-scale trials and long-term follow-up��