摘要 Bullous pemphigoid (BP) is an autoimmune blistering disease that affects patients of advanced age. BP is characterized clinically by tense bullae on the extremities and trunk, histopathologically by subepidermal blisters with eosinophilic infiltration, and immunologically by autoantibodies to BP180 and BP230. Direct immunofluorescence of perilesional skin shows depositions of IgG and C3 in the basement membrane zone[1]. BP rarely shows prominent milia formation, which is a hallmark of epidermolysis bullosa acquisita. We herein describe a 53-year-old man with refractory BP showing numerous milia during recovery.
Introduction
Bullous pemphigoid (BP) is an autoimmune blistering disease that affects patients of advanced age. BP is characterized clinically by tense bullae on the extremities and trunk, histopathologically by subepi-dermal blisters with eosinophilic infiltration, and immunologically by autoantibodies to BP180 and BP230. Direct immunofluorescence of perilesional skin shows depositions of IgG and C3 in the basement membrane zone[1]. BP rarely shows prominent milia formation, which is a hallmark of epidermolysis bullosa acquisita. We herein describe a 53-year-old man with refractory BP showing numerous milia during recovery.
收稿日期: 2018-08-30
出版日期: 2019-01-15
基金资助:Sichuan Province Medical Innovation Project for Youths;Chengdu Technological-Benevolent Project;Chengdu Health and Family Planning Commission Project
通讯作者:
陈涛
E-mail: 13980427003@163.com
引用本文:
张力文 李林 陈涛 王文菊 付丽新 何林. Appearance of prominent milia as secondary lesions during recovery of refractory bullous pemphigoid: a case report[J]. 国际皮肤性病学杂志, 2018, 1(4): 253-255.
Li-Wen Zhang1, Lin Li1, Tao Chen1*, Wen-Ju Wang1, Li-Xin Fu1, Lin He2. Appearance of prominent milia as secondary lesions during recovery of refractory bullous pemphigoid: a case report. International Journal of Dermatology and Venereolo, 2018, 1(4): 253-255.
2018, Vol. 1 
