Disseminated pyoderma gangrenosum with oral involvement: successful treatment with systemic steroids and cyclosporine
Wen-Rui Li1, Bao-Shu Sun2, Nan Sheng1, Si-Jia Zhao1, Wan-Lu Zhang1, Lin Lin1*, Cheng-Rang Li1
1Department of Dermatology, Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China.
2Department of Dermatology, First People’s Hospital of Tancheng, Linyi, Shandong 276199, China.
Introduction
Pyoderma gangrenosum (PG) is a chronic skin disease characterized by progressive lesions that present as painful suppurative ulcers and tend to recur. The pathogenesis of the disease is incompletely under-stood; however, 50% to 70% of affected persons have an associated concomitant systemic disease such as inflammatory bowel disease (IBD)[1]. Any site of the body can be affected; however, involvement of the oropharynx is rare. Here, we present a patient with disseminated PG with oropharyngeal involvement.