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Basal cell carcinoma (BCC) is the most common type of skin cancer. It is preferably located in areas exposed to solar radiation, such as head and neck. It might occur due to long-term ultraviolet radiation, X-ray exposure, ingestion of food or water containing arsenic, immunosuppression, and human papilloma virus (HPV) infection. According to the report of Kiiski et al., patients, who are relatively younger at the first BCC diagnosis, and/or those with a BCC lesion on their upper extremities have a higher risk of developing multiple lesions[1]. Multiple BCC com-bined with different body systems, such as pitted depressions on the hands and feet, odontogenic cysts of the jaws, skeletal abnormalities, intracranial calcification, constituted to the diagnosis of nevoid basal cell carcinoma syndrome (NBCCS). Herein, we presented a case with multiple BCC with giant epidermal cyst and hemangioma.

1Department of Dermatologic Surgery, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Nanjing, Jiangsu 210042, China.
2Department of Dermatology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221000, China.
3Department of Pathology, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Nanjing, Jiangsu 210042, China.

Basal cell carcinoma (BCC) is the most common type of skin cancer. It is preferably located in areas exposed to solar radiation, such as head and neck. It might occur due to long-term ultraviolet radiation, X-ray exposure, ingestion of food or water containing arsenic, immunosuppression, and human papilloma virus (HPV) infection. According to the report of Kiiski et al., patients, who are relatively younger at the first BCC diagnosis, and/or those with a BCC lesion on their upper extremities have a higher risk of developing multiple lesions[1]. Multiple BCC com-bined with different body systems, such as pitted depressions on the hands and feet, odontogenic cysts of the jaws, skeletal abnormalities, intracranial calcification, constituted to the diagnosis of nevoid basal cell carcinoma syndrome (NBCCS). Herein, we presented a case with multiple BCC with giant epidermal cyst and hemangioma.

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