Department of Dermatology, Southwest Hospital, the Third Military Medical University, Chongqing 400038, China.

Introduction Granuloma annulare (GA) is an idiopathic dermis and subcutaneous tissue disease, histologically it is charac-terized by dermal palisading granulomas with central degeneration of collagen. We here report a case of concurrence of localized and subcutaneous GA (SGA) in a 1-year-old girl. Physical examination showed grouped papules merged into an annular pattern in the right ankle and two firm subcutaneous nodules on the dorsal surface of her left foot. Histopathologic exami-nation of lesions on the right ankle showed lympho-cytes and macrophages infiltration in the dermis and increased mucin deposition in the central zone. These features were consistent with localized GA. The nodule on the dorsal surface of the left foot showed degenerated collagen fibers in the areas of central necrobiosis, which were surrounded by a palisade of histiocytes and a minority of lymphocytes. The clinical and histologic findings supported the diagnosis of SGA. As a whole, the patient was diagnosed with localized GA and SGA. The patient was treated with intralesional corticosteroids, and the lesions gradually disappeared during 12-month of follow-up.