�Ϻ���ͨ��ѧҽѧԺ�������ҽԺƤ����

��ժҪ�� ҩ�ﳬ���ۺ����ֳư���������ϸ�������ϵͳ֢״��ҩ���ͨ��ʹ��ijЩҩ��������һ�����ص�ϵͳ��ҩ�ﷴӦ���������ױ�����ҩ�ﳬ���ۺ�������󣬲��ֻ��߳������������Լ�������������򲡡�Graves�����ű���״���ס�����Ǵ��������ۺ��������硢��ֲ��������ȡ������𷢲�����������߲��ķ���������δȷ����Ŀǰ������ҩ�ﳬ���ۺ�����������������߲��ķ���������������Ҫ����������Tϸ�������ƹ���ȱ�ݡ�������Ⱦ��������IJ����ȡ���Ҫ������ҩ�ﳬ���ۺ�����ص����������Լ����Լ������������߲��Ļ��ơ�

Calvina Theresia, Zheng Jie Department of Dermatology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China Corresponding author: Zheng Jie, Email: jie?zheng2001@126.com ��Abstract�� Drug hypersensitivity syndrome, also called drug reaction with eosinophilia and systemic symptoms ��DRESS syndrome��, is a severe systemic adverse drug reaction usually caused by exposure to specific drugs. Several reports have shown that after remission of DRESS syndrome, some patients developed autoimmune diseases, such as type?1 diabetes mellitus, Grave��s disease, Hashimoto��s thyroiditis, lupus erythematosus, sj?gren syndrome, vitiligo, graft?versus host disease ��GVHD�� and other diseases. However, the exact pathogenesis of these autoimmune diseases remains unclear, and mainly involves regulatory T cell dysfunction, virus infection and autoantibody production. This review mainly summarizes DRESS syndrome?related autoimmune diseases and their pathogenesis.