1. ɽ��ʡ��������ҽҽԺ
2. �ൺ��ѧҽѧԺ������̨ع諶�ҽԺ

��ժҪ�� ��������������ݡ��������������߷�ӦΪ������������������������������������ݡ������Ԥ��������Ͼ����������ԣ�����Ŀ��鰷ҩ�����ƺ�����Ч���о����֣���������������ݡ����ķ���ԭ���뿹IgE��������������塢���������Լ�״�ټ����Լ������ݸ˾���Ⱦ���Ŵ����ء��������ص���������йء���������������ݡ���������B�ܰ�ϸ���̼�����ˮƽ���ߣ��̼�������IgE�ĸ��׺������忹��Ϳ�IgE���壬��ʴ�ϸ����Ϻ��շ�����������ݡ���

Lyu Chunpeng*, Kang Erxun. *Qingdao University, Qingdao 266071, China Corresponding author: Kang Erxun, Email: Kangerxun2000@163.com ��Abstract�� The occurrence of chronic autoimmune urticaria ��CAU�� is based on autoimmune responses. CAU with the involvement of autoantibodies shows distinctive prognosis and treatment, and routine antihistamine treatment hardly works. Studies have found that the etiology of CAU is associated with autoantibodies against IgEs and their receptors, autoimmune thyroid diseases, Helicobacter pylori infection, genetic factors, mental factors, etc. In addition, the level of B cell-stimulating factor is elevated in patients with CAU, and it can stimulate the production of antibodies against IgEs and their high-affinity receptors ��anti-FcεRI��, which then bind to mast cells and finally result in the occurrence of urticaria

ɽ��ʡ�Ƽ���չ�ƻ�