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i Dan, Wu Di, Zhou Bingrong, Luo Dan. Department of Dermatology and Venereology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China Corresponding author: Luo Dan, Email: daniluo2005@163.com ��Abstract�� Solar ultraviolet ��UV�� radiation is a ubiquitous carcinogenic environmental factor. Long-term exposure of human skin to UV radiation ��particularly UVA and UVB�� can cause a variety of adverse changes, such as erythema, pigmentation, immunosuppression, photoaging, skin neoplasms, and so on. To avoid these adverse changes and maintain genetic integrity, cells themselves have various protective mechanisms, including DNA repair, cell cycle block and apoptosis induction. Studies have indicated that miRNAs play important roles in various cellular reactions induced by UV radiation, and are associated with a series of adverse cutaneous reactions and dermatoses following UV radiation.

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