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Lu Yuan*, Peng Xiao, Fan Shunping, Liu Shaoxiong, Qu Junle. *Department of Dermatology, Sixth People's Hospital ��Nanshan Hospital�� of Shenzhen, Shenzhen 518052, China Corresponding author: Qu Junle, Email: jlqu@szu.edu.cn ��Abstract�� The development of optical technology has made it possible to perform noninvasive, real-time in vivo biopsy of skin cancer. At present, the most studied optical diagnostic methods in this field include optical coherence tomography, fluorescence spectrometry, diffuse reflectance spectroscopy, Raman spectroscopy, confocal laser scanning microscopy, and so on. Application of these noninvasive optical techniques will increase the accuracy of early diagnosis, and benefit the treatment, of skin cancer.

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