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| PubMed | |
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Article by ZHANG Cheng-guo |
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Article by HUANG Bo |
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Article by FAN Yi-min |
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�㶫ҽѧԺ����ҽԺƤ����, տ��, 524023
���ű�Ӧ�ԽӴ���Ƥ�ķ������ƺͲ������������ʶ������,Ӧ�����ߵ��ڼ����Ƹò����о�Ҳ������.�������ø-4���Ƽ�ͨ������ϸ�����Ӷ�������֢��Ӧ.����ù������������Ƥ�ʼ������,����Ч����ͬ�����,��������Ӧ��С.�������ء��������������ƻ�������,��Ч��ȷ.���ߵ��ڼ�����������,ʹ��������Ϊ���Ʊ�Ӧ�ԽӴ���Ƥ����ѡ��.
Immunomodulatory agents in the treatment of allergic contact dermatitis
Department ofDermatology, Affiliated Hospital of Guangdong Medical College, Zhangjiang 524023, Guangdong, China
Department ofDermatology, Affiliated Hospital of Guangdong Medical College, Zhangjiang 524023, Guangdong, China
Recently,with the progress in the understanding of the pathophysiology and pathogenesis of allergic contact dermatitis,more and more researches are focused on immunomodulatory agents in the treatment of this disease.The inhibitors of phosphodiesterase-4 inhibit the inflammation reaction by regulating cytokine secretion.Compared with glucocorticosteroid,ascomycin has equal or better effects but fewer side effects.Leflunomide and mycophenolate mofeli have similar immunosuppressive mechanism and good therapeutic effects.Given the effects mentioned above,immunomodulatory agents may be used as a new option to treat allergic contact dermatitis.