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| PubMed | |
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Article by XIANG Juan |
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Article by WANG Hua |
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��Ӧ��Ƥ����һ�����Ŵ����������йص����ԡ������ԡ������ԡ���֢��Ƥ������,�䲡����,����������δ��ȷ��������,���Ŷ���Ӧ��Ƥ��ֱ����ص�ЧӦϸ����ЧӦ����,�ر��Ƿʴ�ϸ���������ϸ�����ӵ������о�,����ȷ�ʴ�ϸ������Ӧ��Ƥ����֢������Ǩ�ơ��ۼ����ֲ���������Ļ���,�Լ��ʴ�ϸ����������ϸ����Tϸ��֮������õĹ�ϵ�������������ڽ�һ�������Ӧ��Ƥ��Ƥ����֢��ϸ������,������Ϊ�ٴ������ṩ�µİе㡣
Mast cells in the pathogenesis of atopic dermatitis
Department of Dermatology, Children's Hospital of Chongqing Medical University, Chongqing 400014, China
Department of Dermatology, Children's Hospital of Chongqing Medical University, Chongqing 400014, China
Atopic dermatitis is a pruritic, chronic, recurrent, inflammatory and genetic anaphylactic predisposition-related skin disease with a complex aetiology and unclear pathogenesis. Recently, with the progress in the research on AD-related effector cells and molecules, especially mast cells and their expressing cytokines, it has been gradually clarified about the mechanism of migration, gathering, chemotaxis of mast cells in AD inflammation, as well as the interaction between mast cells, T cells and eosinophils, which will facilitate the understanding of cellular bases of AD inflammation, and provide new targets for AD treatment.
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