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| PubMed | |
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Article by ZHU Qing |
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Article by DIAO Qing-chun |
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Article by BAI Jin |
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Advances in pathogenesis of pruritis in atopic dermatitis
Department of Biomedical Engineering, Institute of Ultrasonic in Medicine, Chongqing University of Medical Sciences, Chongqing 400016, China
Department of Biomedical Engineering, Institute of Ultrasonic in Medicine, Chongqing University of Medical Sciences, Chongqing 400016, China
Pruritus is an essential feature of atopic dermatitis. Because of its severe adverse effects on the quality of life, most of the patients evaluate the severity of atopic dermatitis by the intensity of pruritus rather than appearance of skin lesions. However, its mechanism is not completely understood. Recently, a considerable progress has been achieved in clarifying the complex pathogenesis of pruitus in atopic dermatitis, including the excitation of nervours system and the roles of several mediators. The recent knowledge about the mechanisms may offer new ideas for the treatment of itch in atopic dermatitis.
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