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| PubMed | |
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Article by HANG Yi |
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Article by ZHANG Yi-zhi |
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Advances in subcorneal pustular dermatosis
Department of Dermatology, Huaxi Hospital, Sichuan University, Chengdu 610041, China
Department of Dermatology, Huaxi Hospital, Sichuan University, Chengdu 610041, China
The etiology and pathogenesis of subcorneal pustular dermatosis remain unknown. It may be an autoimmune disease or a subtype of pustular psoriasis, caused by multiple inflammatory factors. Histopathologically, subcorneal pustules with neutrophilic infiltration are the hallmark sign of the disease. It should be differentiated from impetigo, pemphigus foliaceus, dermatitis herpetiformis, pustular psoriasis, acute generalized exanthematous pustulosis and IgA pemphigus, et al. Dapsone is the recommended treatment of this disease. Infliximab and mizoribine are promising to be effective for it, but more clinical trials are still needed.
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