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| PubMed | |
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Article by HE Yu-qing |
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Article by ZHANG Xi-bao |
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Article by ZENG Kang |
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1. ������Ƥ����������, 510095;
2. �Ϸ�ҽ�ƴ�ѧ�Ϸ�ҽԺ
���������۲���һ���ټ��ij�Ⱦɫ�������Ŵ���Ƥ����,�ٴ���Ƥ�����Ƚǻ�Ϊ��Ҫ����,����3���ٴ����͡��䷢����Ҫ��K1��K10��K2e�ǵ�����ͻ������,Ϊ��Ⱦɫ�������Ŵ����ٴ�����֤ʵ,���������ھֲ���ϵͳʹ��άA���,Ƥ��״̬���Ը��ơ��ʹ��������۲��IJ��������ƺ�άA��������û��ƽ���������
Advances on Epidermolytic Hyperkeratosis and Therapeutic Mechanism with Retinoids
Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, China
Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou 510095, China
Epidermolytic hyperkeratosis is a rare autosome dominantly inherited skin disorder with the presentations of erythroderma and hyperkeratosis. Mutations have been found in the genes of keratin 1 (K1), K10 or K2e. The clinical studies confirm that the skin lesions obviously improve with systemic or topical retinoids. The etiology, pathogenesis, and therapeutic mechanism of retiniods in epidermolytic hyperkeratosis are reviewed.
�㶫ʡ��Ȼ��ѧ��������(04004285)
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