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| PubMed | |
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Article by FAN Yi |
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Article by CHEN Hong |
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Role of Estrogen and Its Receptors in the Pathogenesis of SLE
Department of Dermatology, Tianjin Long March Hospital, Tianjin 300021, China
Department of Dermatology, Tianjin Long March Hospital, Tianjin 300021, China
Systemic lupus erythematosus (SLE) is a kind of autoimmunity disease caused by complicated factors. Estrogen and its receptors play an important role in the pathogenesis of SLE. Recently, great progress has been made in the research of their action mechanisms at molecular biologic and genetic levels. This article presents various possible mechanisms of estrogen and its receptors in the pathogenesis of SLE and updated progresses in their clinical research, which may provide new approaches to the research and treatment of SLE.
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