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PubMed
Article by YU Bing
Article by WENG Rui-quan
Article by LI Hui

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Dendritic Cells in Sexually Transmitted Diseases and AIDS

Department of Dermatology and Venereology, Second Affiliated Hospital of Chongqing University of Medical Sciences, Chongqing 400010, China

Department of Dermatology and Venereology, Second Affiliated Hospital of Chongqing University of Medical Sciences, Chongqing 400010, China

Abstract:

Dendritic cells (DCs) are considered to be the most potent professional antigen-presenting cells in vivo,and their antigen-presenting ability is 10 to 100 times that of macrophages. DCs can efficiently activate T and B lymphocytes,and build an organic connection between the innate and adaptive immunity. Numbers of researches have revealed that DCs play an important role in anticancer and anti-infection effect, graft rejection reaction, and autoimmune diseases. Recently,DCs have been reported to be involved in venereal diseases,i.e. AIDS,syphilis,condyloma acuminatum and genital herpes,etc. This review summarizes recent progress on DC differentiation,immunological activities, and research progress in common venereal diseases.

Keywords: Dendritic cells   Sexually transmitted disease   Acquired immunodeficiency syndrome   Syphilis   Condylomata acuminata   Herpes, genitalis  
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