[an error occurred while processing this directive] ����Ƥ���Բ�ѧ��־ 2006, 32(3) 176-178 DOI:     ISSN: 2096-5540 CN: 32-1880/R

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PubMed
Article by ZHANG Cai-ping
Article by CUI Pan-gen

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Evaluation of the Efficacy of Antihistamines in the Treatment of Chronic Urticaria Using Human Monocyte-derived Dendritic Cells

Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, China

Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, China

Abstract:

Chronic urticaria is a very common skin disease. It is easy to diagnose but difficult to treat. Antihistamines are the drugs of first choice, however, some patients show indefinite responses to them. There is still no objective index to assess the efficacy of antihistamines. We review the function of dendritic cells in allergic diseases and the progress in experiments evaluating the efficacy of antihistamines by human monocyte-derived dendritic cells, to provide a platform for evaluating the efficacy of antihistamines in the treatment of chronic urticaria.

Keywords: Urticaria   Histamine H1 antagonists   Dendritic cells  
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