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| PubMed | |
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Article by JI Xi |
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Article by LUO Dan |
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�Ͼ�ҽ�ƴ�ѧ��һ����ҽԺƤ���� 210029
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Macrophage Migration Inhibitory Factor and Its Relation with SMn Diseases
Department of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
Department of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
Macrophage migration inhibitory factor(MIF), produced by many kinds of cells, is a pro-inflammatory cytokine. Also, it is a pituitary-derived hormone and a negative feedback regulator of glucocorticoid activity. With the development of molecular cloning of MIF cDNA and elucidation of its structure, MIF is being increasingly recognized for its special biological properties and function in many dermatoses. Since MIF can inhibit the movement of macrophages, it plays an important role in the initiation and development of many dermatoses.
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