|
��չ����
|
|
| ������Ϣ | |
 |
Supporting info |
|
PDFȫ�� |
|
[HTMLȫ��] |
|
����� |
| �����뷴�� | |
|
�������ù����� |
|
���� |
|
Email Alert |
|
���·��� |
|
���������Ϣ |
| ���Ĺؼ���������� | |
|
������ |
|
ҩ���Ʒ� |
| ��������������� | |
|
���� |
|
�Ÿ��� |
|
����� |
| PubMed | |
|
Article by TIAN Fu-jun |
|
Article by ZHANG Fu-ren |
|
Article by ZHAO Tian-en |
�����Ǿֲ�ҩ�����ƽ�չ
����, �Ÿ���, �����
ɽ��ʡƤ�����Բ������о��� ���� 250022
�������Ƿ����������˱Dz����沿��һ��������֢��Ƥ���������������ڸ�������������ʧ����ëϸѪ�ܳ����������¡�������������һ�����ڵĹ���,����ϵͳ��ҩ�����������Ӧ,����,���о�����,ϵͳ��ҩ������ҩ�����ƾ�����ͬ����Ч�����,�ٴ��϶�ѡ�þֲ�ҩ�����ơ�
Topical Therapy for Rosacea
Shandong Provincial Institute of Dermatology and Venereology, Jinan 250022, China
Shandong Provincial Institute of Dermatology and Venereology, Jinan 250022, China
Rosacea is a chronic inflammatory dermatosis occurring on the face and nose of middle-aged persons. Vasomotor lability, maladjustment of nervous system function and longstanding telangiectases caused by various factors all contribute to the pathogenesis of rosacea. The therapy of rosacea is a long-term process. Systemic treatment for rosacea often has many side effects and the efficacy of it is similar to that of the topical treatment. Therefore rosacea sufferers prefer topical drugs. This article reviews the topical therapy for rosacea.
[2] Wolf JE Jr.The role of topical metronidazole in the treatment of rosacea.Cutis,2004,73 (1 Suppl):19-28.
[3] Dahl MV,Jarratt M,Kaplan D,et al.Once-daily topical metronidazole cream formulations in the treatment of the papules and pustules of rosacea.J Am Acad Dermatol,2001,45:723-730.
[4] Tan JK,Girard C,Krol A,et al.Randomized placebo-controlled trial of metronidazole 1% cream with sunscreen SPF 15 in treatment of rosacea.J Cutan Med Surg,2002,6:529-534.
[5] Kocak M,Yagli S,Vahapoglu G,et al.Permethrin 5% cream versus metronidazole 0.75% gel for the treatment of papulopustular rosacea.A randomized double-blind placebo-controlled study.Dermatology,2002,205:265-270.
[6] Elewski BE,Fleischer AB Jr,Pariser DM.A comparison of 15%azelaic acid gel and 0.75% metronidazole gel in the topical treatment of papulopustular rosacea:results of a randomized trial.Arch Dermatol,2003,139:1444-1450.
[7] Thiboutot D,Thieroff-Ekerdt R,Graupe K.Efficacy and safety of azelaic acid (15%) gel as a new treatment for papulopustular rosacea:results from two vehicle-controlled,randomized phase ��studies.J Am Acad Dermatol,2003,48:836-845.
[8] Frampton JE,WagstaffAJ.Azelaic acid 15% gel:in the treatment of papulopustular rosacea.Am J Clin Dermatol,2004,5:57-64.
[9] Sauder DN,Miller R,Gratton D,et al.The treatment of rosacea:the safety and efficacy of sodium sulfacetamide 10% and sulful5% lotion (Novacet) is demonstrated in a double-blind study.J Dermatol Treat,1997,8:79-85.
[10] Del Rosso JQ.Evaluating the role of topical therapies in the management of rosacea:focus on combination sodium sulfacetamide and sulfur formulations.Cutis,2004,73 (1 Suppl):29-33.
[11] Bamford JT,Elliott BA,Haller ��.Tacrolimus effect on rosacea.J Am Acad Dermatol,2004,50:107-108.
[12] Stuetz A,Grassberger M,Meingassner JG.Pimecrolimus (Elidel,SDZ ASM 981)-preclinical pharmacologic profile and skin selectivity.Semin Cutan Med Surg,2001,20:233-241.
[13] Chu CY.The use of 1% pimecrolimus cream for the treatment of steroid-induced rosacea.Br J Dermatol,2005,152:396-399.
[14] Ozturkcan S,Ermertcan AT,Sahin MT,et al.Efficiency of benzoyl peroxide-erythromycin gel in comparison with metronidazole gel in the treatment of acne rosacea.J Dermatol,2004,31:610-617.
[15] Breneman D,Savin R,VandePol C,et al.Double-blind,randomized,vehicle-controlled clinical trial of once-daily benzoyl peroxide/clindamycin topical gel in the treatment of patients with moderate to severe rosacea.Int J Dermatol,2004,43:381-387.
[16] Leyden JJ,Thiboutot D,Shalita A.Photographic review of results from a clinical study comparing benzoyl peroxide 5%/clindamycin1% topical gel with vehicle in the treatment of rosacea.Cutis,2004,73(6 Suppl):11-17.
[17] ones D.Reactive oxygen species and rosacea.Cutis,2004,74 (3Suppl):17-20,32-4.
[18] Wozniacka A,Sysa-Jedrzejowska A,Adamus J,et al.Topical application of NADH for the treatment of rosacea and contact dermatitis.Clin Exp Dermatol,2003,28:61-63.
[19] McHugh RC,Rice A,Sangha ND,et al.A topical azithromycin preparation for the treatment of acne vulgaris and rosacea.J Dermatolog Treat,2004,15:295-302.
[20] Heymann WR.Rosacea subtype-directed therapy.J Am Acad Dermatol,2004,51:90-92.