[an error occurred while processing this directive] ����Ƥ���Բ�ѧ��־ 2004, 30(4) 247-249 DOI:     ISSN: 2096-5540 CN: 32-1880/R

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[11] Mason CS, Springer CJ, Cooper RG,et al. Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation. EMBO J,1999, 18:2137-2148.
[12] Busca R, Abbe P, Mantoux F, et al. Ras mediates the cAMP-de-pendent activation of extracellular signal-regulated kinases (ERKs) in melanocytes. EMBO J, 2000, 19:2900-2910.
[13] Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature, 2002,417:949-954.
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[16] Dong J, Phelps RG, Qiao R, et al. BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma. Cancer Res, 2003, 63(14):3883-3885.
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