[an error occurred while processing this directive] | ����Ƥ���Բ�ѧ��־ 2004, 30(2) 88-90 DOI: ISSN: 2096-5540 CN: 32-1880/R | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
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1. ���ϴ�ѧ���Ŷ�ҽԺƤ����, ��ɳ 410011; | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
1. ���ϴ�ѧ���Ŷ�ҽԺƤ����, ��ɳ 410011; | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
Keywords: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
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DOI: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
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[1] lhn H. The role of TGF-beta signaling in the pathogenesis of fibrosis in scleroderma. Arch Immunol Ther Exp(Warsz), 2002, 50(5):325-331. [2] Brigstock DR, Goldschmeding R, Katsube KI, et al. Proposalfor a unified CCN nomenclature. Mol Pathol, 2003, 56(2):127-128. [3] Brigstock DR. The connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed(CCN)family. Endocr Rev, 1999, 20(2):189-206. [4] Bradham DM, Igarashi A, Potter RL, et al. Connective tissue growth factor:a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J Cell Biol, 1991, 114(6):1285-1294. [5] Grotendorst GR, Okochi H, Hayashi N. A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene. Cell Growth Differ, 1996, 7(4):469. [6] Frazier K, Williams S, Kothapalli D, et al. Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor. J Invest Dermatol, 1996, 107(3):404-411. [7] Grotendorst GR. Connective tissue growth factor:a mediator of TGFbeta action on fibroblasts. Cytokine Growth Factor Rev, 1997, 8(3):171-179. [8] Duncan MR, Frazier KS,Abramson S,et al. Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis:down-regulation by cAMP. FASEB J, 1999, 13(13):17746. [9] Querfeld C, Eckes B, Huerkamp C, et al. Expression of TGF-beta 1,beta 2 and-beta 3 in localized and systemic scleroderma. J Dermatol Sci, 1999, 21(1):13-22. [10] Igarashi A, Nashiro K, Kikuchi K, et al. Significant correlation between connective tissue growth factor gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis. J Invest Dermatol, 1995, 105(2):280-284. [11] Igarashi A, Nashiro K, Kikuchi K, et al. Connective tissue growth factor gene expression in tissue sections from localized scleroderma,keloid, and other fibrotic skin disorders. J Invest Dermatol, 1996,106(4):729-733. [12] Quan T, He T, Kang S, et al. Connective tissue growth factor:expression in human skin in vivo and inhibition by ultraviolet irradiation. J Invest Dermatol, 2002, 118(3):402-408. [13] Sato S, Nagaoka T, Hasegawa M, et al. Serum levels of connective tissue growth factor are elevated in patients with systemic sclerosis:association with extent of skin sclerosis and severity of pulmonary fibrosis. J Rheumatol, 2000, 27(1):149-154. [14] Mori T, Kawara S, Shinozaki M, et al. Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis:A mouse fibrosis model. J Cell Physiol, 1999, 181(1):153-159. [15] Chen CC, Chen N, Lau LF. The angiogenic factors Cyr 61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts. J Biol Chem, 2001,276(13):10443-10452. [16] Maeda S, Dean DD, Gay I,et al. Activation of latent transforming growth factor betal by stromelysin 1 in extracts of growth plate chondrocyte-derived matrix vesicles. J Bone Miner Res, 2001, 16(7):1281-1290. [17] Nabel EG, Shum L, Pompili VJ, et al. Direct transfer of transforming growth factor beta 1 gene into arteries stimulates fibrocellular hyperplasia. Proc Natl Acad Sci U S A, 1993, 90(22):10759-10763. [18] Jedsadayanmata A, Chen CC, Kireeva ML, et al. Activation-dependent adhesion of human platelets to Cyr 61 and Fisp 12/mouse connective tissue growth factor is mediated through integrin alpha(��b)beta(3). J Biol Chem, 1999, 274(34):24321-24327. [19] Leask A, Sa S, Holmes A, et al. The control of con 2 (ctgf)gene expression in normal and scleroderma fibroblasts. Mol Pathol, 2001,54(3):180-183. [20] Holmes A, Abraham DJ, Sa S, et al. CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling. J Biol Chem, 2001,276(14):10594-10601. [21] Leask A, Holmes A, Black CM, et al. Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts. J Biol Chem, 2003, 278(15):130085. |
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3����ϼ, ����.ϵͳ��ӲƤ�����Ƶ��о���չ[J]. ����Ƥ���Բ�ѧ��־, 2003,29(3): 138-140 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
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