|
��չ����
|
|
| ������Ϣ | |
 |
Supporting info |
|
PDFȫ�� |
|
[HTMLȫ��] |
|
����� |
| �����뷴�� | |
|
�������ù����� |
|
���� |
|
Email Alert |
|
���·��� |
|
���������Ϣ |
| ���Ĺؼ���������� | |
|
�����ҩ |
|
ҩ������,��� |
| ��������������� | |
|
���㷼 |
|
����Ƽ |
| PubMed | |
|
Article by |
|
Article by |
�����ҩ�����о���״
���㷼, ����Ƽ
����ҽѧԺ��һ����ҽԺƤ���� 650032
������,���������ҩ�������������,������Ƶ��о����������롣����Ϊ�����ҩ������Ҫ�뿹���ҩ�����õİ�λ��ṹ��/���ܵĸı�,ҩ����ϸ���ڵ���������йء��������ؽ��������������Ƶ��о���չ,��̽�ֿ˷������ҩ�ԵĴ�ʩ��������⡣
[2] vanden Bossche H,Marichal P,Odds FC,et al.Characterization of an azole-resistant Candida glabrata isolate.Antimicrob Agents Chemother,1992,36(12):9602-2610.
[3] Ghannoum MA,Rice LB.Antifungal agents:mode of action,mechanisms of resistance,and correlation of these mechanisms with bacterial resistance.Clin Microbiol Rev,1999,12(4):501-517.
[4] White TC,Marr KA,Bowden RA.Clinical,cellular,and molecular factors that contribute to antifungal drug resistance.Clin Microbiol Rev,1998,11(2):382-409.
[5] Kakeya H,Miyazaki Y,Miyazaki H,et al.Genetic analysis of azole resistance in the Darlington strain of Candida albicans.Antimicrob Agents Chemother,9000,44(11):2985-2990.
[6] Kohli A,Smriti,Mukhopadhyay K,et al.In vitro low-level resistance to azoles in Candida albicans is associated with changes in membrane lipid fluidity and asymmetry.Antimicrob Agents Chemother,2002,46(4):1046-1052.
[7] Emter R,Heese-Peck A,Kralli A.ERG6 and PDR5 regulate small lipophilic drug accumulation in yeast cells via distinct mechanisms.FEBS Lett,2002,591(1-3):57-61.
[8] Akache B,Turcotte B.New regulators of drug sensitivity in the family of yeast zinc cluster proteins.J Biol Chem,2002,277(24):21254-21260.
[9] Hellauer K,Akache B,MacPherson S,et al.Zinc cluster protein Rdrl p is a transcriptional repressor of the PDR5 gene encoding a multidrug transporter.J Biol Chem,2002,277(20):17671-17676.
[10] St Georgiev V.Membrane transporters and antifungal drug resistance.Curr Drug Targets,2000,1(3):261-284.
[11] Sanglard D,Iseher F,Monod M,et al.Cloning of Candida albicans genes conferring resistance to azole antifungal agents:characterization of CDR2,a new multidrug ABC transporter gene.Microbiology,1997,143(Pt 2):405-4-16.
[12] de Mieheli M,Bille J,Schueller C,et al.A common drug-responsive element mediates the upregulation of the Candida albieans ABC transporters CDR1 and CDR2,two genes involved in antifungal drug resistance.Mol Mierobiol,2002,43(5):1197-1214.
[13] Sanglard D,Ischer F,Bille J.Role of ATP-binding-cassette transporter genes in high-frequency acquisition of resistance to azole antifungals in Candida glabrata.Antimicrob Agents Chemother.2001,45(4):1174-1183.
[14] Katiyar SK,Edlind TD.Identification and expression of multidrug resistance-related ABC transporter genes in Candida krusei.Med Mycol,2001,39(1):109-116.
[15] Perea S,Lopez-Ribot JL,Wickes BL,et al.Molecular mechanisms of fluconazole resistance in Candida dubliniensis isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis.Antimicrob Agents Chemother,2002,46(6):1695-1703.
[16] Sanglard D,Ischer F,Monod M,et al.Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors.Antimicrob Agents Chemother,1996,40(10):2300-2305.
[17] Wirsching S,Moran GP,Sullivan DJ,et al.MDRI-mediated drug resistance in Candida dubliniensis.Antimicrob Agents Chemother,2001,45(12):3416-3421.
[18] De Backer MD,llyina T,Ma XJ,et al.Genomic profiling of the response of Candida albicans to itraconazole treatment using a DNA microarray.Antimierob Agents Chemother,2001,45(6):1660-1670.
[19] Perea S,Lopez-Ribot JL,Kirkpatrick WR,et al.Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patients.Antimicrob Agents Chemother,2001,45(10):2676-2684.
[20] White TC.Increased mRNA levels of ERG16,CDR,and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus.Antimicrob Agents Chemother,1997,41(7):1482-1487.
[21] Kurtz MB,Douglas CM.Lipopeptide inhibitors of fungal glucan synthase.J Med Vet Mycol,1997,35(2):79-86.