|
��չ����
|
|
| ������Ϣ | |
 |
Supporting info |
|
PDFȫ�� |
|
[HTMLȫ��] |
|
����� |
| �����뷴�� | |
|
�������ù����� |
|
���� |
|
Email Alert |
|
���·��� |
|
���������Ϣ |
| ���Ĺؼ���������� | |
|
һ������ |
|
һ��������ø |
|
��ɫ���� |
| ��������������� | |
|
�վ� |
|
Ϳ��ͥ |
| PubMed | |
|
Article by |
|
Article by |
һ��������һ��������ø����Ժ�����
�վ�, Ϳ��ͥ
���пƼ���ѧͬ��ҽѧԺ����Э��ҽԺƤ���� �人 430030
һ��������Ϊһ����Ҫ����ʹ��ЧӦ����,�����˶��Ժ�������������չ��ת�Ƶȹ��̡�Ŀǰ���о�����һ��������ø�ڶ��Ժ������еı�Ｐ���Ծ������ϵ�,��ϳɵ�һ�������ڲ�ͬ���������ӵ����Ϳ��������ٽ�ת�ƺ�����ת�Ƶȶ���ЧӦ���ӷ���ˮƽ�������һ��������һ��������ø�ڶ��Ժ�����������,��Ϊ�о��䷢�����ơ����ƴ����µ�������ϣ����
[2] Goto T,Haruma K,Kitadai Y,et al.Enhanced expression of inducible nitric oxide synthase and nitrotyrosine in gastric mucosa of gastric cancer patients.Clin Cancer Res,1999,5(6):1411-1415.
[3] Massi D,Franchi A,Sardi I,et al.Inducible nitric oxide synthase expression in benign and malignant cutaneous melanocytic lesions.J Pathol,2001,194(2):194-200.
[4] Ekmekcioglu S,Ellerhorst J,Smid CM,et al.Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival.Clin Cancer Res,2000,6(12):4768-4775.
[5] Ahmed B,Van Den Oord JJ.Expression of the inducible isoform of nitric oxide synthase in pigment cell lesions of the skin.Br J Derma-tol,2000,142(3):432-440.
[6] Salvucci O,Carsana M,Bersani I,et al.Antiapoptotic role of endogenous nitric oxide in human melanoma cells.Cancer Res,2001,61(1):318-326.
[7] Tendler DS,Bao C,Wang T,et al.Intersection of interferon and hypexia signal transduction pathways in nitric oxide-induced tumor apeptosis.Cancer Res,2001,61(9):3682-3688.
[8] Xie K,Huang S,Dong Z,et al.Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells.J Exp Med,1995,181(4):1333-1343.
[9] Fecker LF,Eberle J,Orfanos CE,et al.Inducible nitric oxide synthase is expressed in normal human melanocytes but not in melanoma cells in response to tumor necrosis factor-alpha,interferon-gamma,and lipepelysaccharide.J Invest Dermatol,2002,118(6):1019-1025.
[10] Juang SH,Xie K,Xu L,et al.Use of retroviral vectors encoding murine inducible nitric oxide synthase gene to suppress tumorigenicity and cancer metastasis of murine melanoma.Cancer Biother Radiopharm,1997,12(3):167-175.
[11] lshii Y,Ogura T,Tatemichi M,et al.Induction of matrix metalloproteinase gene transcription by nitric oxide and mechanisms of MMP-1gene induction in human melanoma cell lines.Int J Cancer,2003,103(2):161-168.
[12] Zhang XM,Xu Q.Metastatic melanoma cells escape from immunosurveillanee through the novel mechanism of releasing nitric oxide to induce dysfunction of immunocytes.Melanoma Res,2001,11(6):559-567.
[13] Konopka TE,Barker JE,Bamford TL,et al.Nitric oxide synthase�� gene disruption:implications for tumor growth and vascular endothelial growth factor production.Cancer Res,2001,61(7):3182-3187.
[14] Ekmekcioglu S,Ellerhorst JA,Mumm JB,et al.Negative association of melanoma differentiation-associated gene(mda-7)and Inducible nitric oxide synthase(iNOS)in human melanoma:MDA-7 regulates iNOS expression in melanoma cells.Mol Cancer Ther,2003,2(1):9-17.
[15] Wang HH,McIntosh AR,Hasinoff BB,et al.Regulation of B16F1melanoma cell metastasis by inducible functions of the hepatic microvaseulature.Eur J Cancer,2002,38(9):1261-1270.
[16] Xie K,Bielenberg D,Huang S,et al.Abrogation of tumorigenicity and metastasis of murine and human tumor cells by transfection with the murine IFN-beta gene:possible role of nitric oxide.Glin Cancer Res,1997,(12Pt1):2283-2294.
[17] Dong Z,Qi X,Xie K,et al.Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaecharideresponsive and lipopolysaccharide-nonresponsive murine macrophages.J lmmunol,1993,151(5):2717-2724.
[18] Joshi M,Strandhoy J,White WL.Nitric oxide synthase activity is upregulated in melanoma cell lines:a potential mechanism for metastases formation.Melanoma Res,1996,6(2):121-126.
[19] Qiu H,Orr FW,Jensen D,et al.Arrest of B16 melanoma cells in the mouse pulmonary microeirculation induces endothelial nitric oxide synthase-dependent nitric oxide release that is cytotoxic to the tumor cells.Am J Pathol,2003,162(2):403-412.
[20] Ahmed B,Van Den Oord JJ.Expression of the neuronal isofonn of nitric oxide synthase(nNOS)and its inhibitor,protein inhibitor of nNOS,in pigment cell lesions of the skin.Br J Dermatol,1999,141(1):12-19.
[21] Matthews NE,Adams MA,Maxwell LR,et al.Nitric oxide-mediated regulation of chemosensitivity in cancer cells.J Natl Cancer Inst,2001,93(24):1879-1885.