|
��չ����
|
|
| ������Ϣ | |
 |
Supporting info |
|
PDFȫ�� |
|
[HTMLȫ��] |
|
����� |
| �����뷴�� | |
|
�������ù����� |
|
���� |
|
Email Alert |
|
���·��� |
|
���������Ϣ |
| ���Ĺؼ���������� | |
|
����,����Ĥĸϸ���� |
|
��ͷ״������,�� |
|
���� |
| ��������������� | |
|
��Сǿ |
|
Ϳ��ͥ |
| PubMed | |
|
Article by |
|
Article by |
Rb������HPV�������
��Сǿ, Ϳ��ͥ
���пƼ���ѧͬ��ҽѧԺЭ��ҽԺƤ���� �人 430022
����Ĥĸϸ����������ϸ�����ڵ����������,��һ����Ҫ���ְ�����.����Ĥĸϸ��������ṹ�쳣������ͷ����������������ټ�.����ͷ���������ڵ���7������Ĥĸϸ���������,ת¼��������,��������Ĥĸϸ������������ʧ��.����ͷ���������ڵ���7��������Ĥĸϸ��������������������������������,������д���һ������.
[2] Nishinaka T,Fu YH,Chen LI,et al.A unique cathepsin-like protease isolated from CV-1 cells is involved in rapid degradation of retinoblastoma susceptibility gene product,RB,and transcription factor SP1.Biochim Biophys Acta,1997,1351(3):274-286.
[3] Fang X,Jin X,Xu HJ,et al.Expression of p16 induces transcriptional downregulation of the RB gene.Oncogene,1998,16(1):1-8.
[4] Ishiji T.Molecular mechanism of carcinogenesis by human papillomavirus-16.J Dermatol,2000,27(2):73-86.
[5] Cooper K,Herrington CS,Stickland JE,et al.Episomal and integrated human papillomavirus in cervical neoplasia shown by non-isotopic in situ hybridisation.J Clin Pathol,1991,44(12):990-996.
[6] Wang P,Peng ZL,Wang H,et al.Study on the carcinogenic mechanism of human papilomavirus typel6 E7 protein in cervical carcinoma.J Exp Clin Virol,2000,14(2):117-120.
[7] Boyer SN,Wazer DE,Band V.E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.Cancer Res,1996,56(20):4620-4624.
[8] Alunni-Fabbroni M,Littlewood T,Deleu L,et al.Induction of S phase and apoptosis by the human papillomavirus type 16 E7 protein are separable events in immortalized rodent fibroblasts.Oncogene,2000,19(19):2277-2285.
[9] Giarre M,Caldeira S,Malanchi I,et al.Induction of pRb degradation by the human papillomavirus type 16 E7 protein is essential to efficiently overcome p16INK4a-imposed G1 cell cycle Arrest.J Virol,2001,75(10):4705-4712.
[10] Milde-Langosch K,Riethdorf S,Kraus-Poppinghaus A,et al.Expressioo of cyclin-dependent kinase inhibitors p16MTS1,p21WAF1,and p27KIP1 in HPV-positive and HPV-negative cervical adenocarcinomas.Virchows Arch,2001,439(1):55-61.
[11] Choo KB,Chong KY.Absence of mutation in the p53 and the retinoblastoma susceptibility genes in primary cervical carcinomas.Virology,1993,193(2):1042-1046.
[12] Zhao W,Yu X,Zhou Y,et al.Rb gene and HpV-16 E7 oncogene in cervical squamous cell carcinoma.Acta Acad Med SHAN DoNG,1997,35:290-293.
[13] Kim JW,Lee CG,Han SM,et al.Loss of heterozygosity of the retinoblastoma and p53 genes in primary cervical carcinomas with human papillomavirus infection.Gynecol Oncol,1997,67(2):215-221.
[14] Mathevet P,Frappart L,Hittelman W.Cervix dysplasias:study of Rb and p53 gene expression and correlation with mitotic activity.Gynecol Obstet Fertil,2000,28(1):44-50.
[15] Arany I,Rady P,Tyring SK.Alterations in cytokine/antioncogene expression in skin lesions caused by "low-risk" types of human papillomaviruses.Viral Immunol,1993,6(4):255-265.
[16] Schell BJ,Rosen T,Rady P,et al.Verrucous carcinoma of the foot associated with human papillomavirus type 16.J Am Acad Dermatol,2001,45(1):49-55.
[17] Andl T,Kahn T,Pfuhl A,et al.Etiological involvement of oncogenic human papillomavirus in tonsillar squamous cell carcinomas lacking retinoblastoma cell cycle control.Cancer Res,1998,58(1):5-13.
[18] Gupta D,Holden J,Layfield L.Topoisomerase alpha ��,retinoblastoma gene product,and p53:potential relationships with aggressive behavior and malignant transformation in recurrent respiratory papillomatosis.Appl Immunohistochem Mol Morphol,2001,9(1):86-91.