|
��չ����
|
|
| ������Ϣ | |
 |
Supporting info |
|
PDFȫ�� |
|
[HTMLȫ��] |
|
����� |
| �����뷴�� | |
|
�������ù����� |
|
���� |
|
Email Alert |
|
���·��� |
|
���������Ϣ |
| ���Ĺؼ���������� | |
|
HIV-1 |
|
ת¼���� |
|
��������� |
|
�������,tat |
| ��������������� | |
|
�� |
|
���� |
| PubMed | |
|
Article by |
|
Article by |
HIV-1ת¼���ػ��Ƶ��о���չ
��, ����
�й�ҽѧ��ѧԺ���й�Э��ҽ�ƴ�ѧƤ�����о���, �Ͼ�210042
HIV-1��һ�������������,���ɳ���DZ��,�ֿ�Ѹ���ƻ���������HIV-1���ƵĶ���Կ���������ص�ת¼���ڻ��ƾ����ġ�HIV-1�����ת¼���ڹ����漰���ܶ�����,����ϸ������ת¼���ӡ�������ĩ���ظ�����ָ������ת¼Ч���йص�ת¼���ӡ�Tat���ס�HIV-1������5������ĩ���ظ������е�˳ʽ����Ԫ���ͷ�Ӧ����Ӧ��Ԫ����,�Լ�����֮�������á�
[2] Majello B, Napo1litano G, De Luca P, et al. Recruitment of human TBP selectively activates RNA polymerase �� TATA-dependent promoters. J Biol Chem. 1998, 273(26):16509-16516.
[3] Zenzie-Gregory B, Sheridan P, Jones KA, etal. HIV-1 core promoter lacks a simple initiator element but contains a bipartite activator at the transcription start site. J Biol Chem, 1993, 268 (21):15823-15832.
[4] Sune C, Garcia-Blanco MA. Spl transcription factor is required for in vitro basal and Tat-activated transcription from the human immunodeficiency virus type 1 long terminal repeat. J Virol. 1995,69(10):6572-6576.
[5] Kretzschmar M, Meisterernst M, Scheidereit C, et al. Transcriptional regulation of the HIV-1 promoter by NF-kappa B in vitro. Genes Dev, 1992, 6(5):761-774.
[6] Takada N, Sanda T, Okamoto H, et al. RelA-associated inhibitor blocks transcription of human immunodeficiency virus type 1 by inhibiting NF-kappaB and Sp1 actions. J Virol, 2002, 76 (16):8019-8030.
[7] Fujii R, Okamoto M, Aratani S, et al. A Role of RNA Helicase A in cis-Acting Transactivation Response Element-mediated Transcriptional Regulation of Human Immunodeficiency Virus Type I. J Biol Chem, 2001, 276(8):5445-5451.
[8] Chen-Park FE, Huang DB, Noro B, et al. The kappa B DNA se quence from the HIV long terminal repeat functions as an allosteric regulator of HIV transcription. J Biol Chem. 2002, 277 (27):24701-24708.
[9] Al-Harthi L, Roebuck KA. Human immunodeficiency virus type-1 transcription:role of the 5'-untranslated leader region (review). Int J Mol Med, 1998, 1(5):875-881.
[10] Wei P, Garber ME, Fang SM, et al. A novel CDK9-associated C type cyclin interacts directly with HIV-1 Ta and mediates its high-affinity, loop-specific binding to TAR RNA. Cell. 1998,92 (4):451-462.
[11] Tasara T, Hottiger MO, Hubscher U. Functional genomics in HIV-1 virus replication:protein-protein interactions as a basis for recruiting the host cell machinery for viral propagation. Biol Chem, 2001, 382 (7):993-999.
[12] Garber ME, Wei P, KewalRamani VN, et al. The interaction betweenHIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein. Genes Der, 1998, 12(22):3512-3527.
[13] Price DH. P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase ��. Mol Cell Biol, 2000, 20(8):2629-2634.
[14] Kim YK, Bourgeois CF. Isel C, et al. Phosphorylation of the RNA polymerase �� carboxyl-terminal domain by CDK9 is directly responsi ble for human immunodeficiency virus type 1 Tat-activated transcriptional elongation. Mol Cell Biol, 2002, 22(13):4622-4637.
[15] Garber ME, Mayall TP, Suess EM, et al. CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA. Mol Cell Biol, 2000, 20 (18):6958-6969.
[16] Nekhai S, Zhou M, Fernandez A, et al. HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat-mediated transcription. Biochem J, 2002, 364 (Pt 3):649-657.
[17] Barboric M. Nissen RM, Kanazawa S, et al. NF-kappaB binds P-TE Fb to stimulate transcriptional elongation by RNA polymerase ��. Mol Cell, 2001, 8(2):327-337.
[18] Yang Z, Zhu Q, Luo K,et al. The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription. Nature, 2001. 414(6861):317-322.
[19] Cook JA, August A. Henderson AJ. Recruitment of phosphatidylinosi tol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism. J Immunol, 2002, 169(1):254-260.
[20] Jordan A, Defechereux P, Verdin E. The site of HIV-1 integration in the human genome determines basal transcriptional activity and re sponse to Tat transactivation. EMBO J, 2001,20(7):1726-1738.