[an error occurred while processing this directive] ����Ƥ���Բ�ѧ��־ 2003, 29(2) 106-109 DOI:     ISSN: 2096-5540 CN: 32-1880/R

����Ŀ¼ | ����Ŀ¼ | ������� | �߼�����                                                            [��ӡ��ҳ]   [�ر�]
����
��չ����
������Ϣ
Supporting info
PDFȫ��
[HTMLȫ��]
�����
�����뷴��
�ѱ����Ƽ�������
�����ҵ����
�������ù�����
����
Email Alert
���·���
���������Ϣ
���Ĺؼ����������
Toll������
֬������
��������
���������������
����
֣��
PubMed
Article by
Article by

Toll����������������

��С��, ֣��

�Ϻ��ڶ�ҽ�ƴ�ѧ�������ҽԺƤ����, 200025

ժҪ��

Toll���������½����ֵĴ����ڲ����ද��ϸ�����桢�����źŴ����Ŀ�Ĥ����,��һ���������Ӧ�����Ҫ���ӡ����о�Toll������ļ����Ա�ͽṹ�ص㡢����ʶ��ԭ΢����Ͳ��빹���źŴ������帴���������������߹����з������á��������ٴ���������ڵ���ϵ������������Toll������ķ��ֺ���ʶ��Ϊ�����о���Ⱦ�Լ����Լ����������Ժͱ�̬��Ӧ�Լ����ķ��������ṩ����,Ϊ��Щ�����������ṩ�µ�˼·���ֶΡ�

�ؼ����� Toll������   ֬������   ��������  

Abstract:

Keywords:
�ո����� 2002-04-09 �޻�����  ����淢������  
DOI:
������Ŀ:

ͨѶ����:
���߼��:

�ο����ף�
[1] Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature, 1997,388 (6640):394-397.
[2] Hallman M, Ramet M, Ezekowitz RA. Toll-like receptors as sensors of pathogens. Pediatr.Res, 2001,50(3):315-321.
[3] Matsuguchi T, Musikacharoen T, Ogawa T, et al. Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages. J Immunol, 2000, 165 (10):5767-5772.
[4] Tapping RI, Akashi S, Miyake K, et al. Toll-like receptor 4, but not toll-like receptor 2, is a signaling receptor for Escherichia and Salmo nella lipopolysaccharides. J Immunol, 2000, 165 (10):5780-5787.
[5] Shimazu R, Akashi S, Ogata H, et al. MD-2, a molecule that con fers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med, 1999, 189(11):1777-1782.
[6] Muzio M, Polentarutti N, Bosisio D, et al. Toll-like receptor family and signalling pathway. Biochem Soc Trans, 2000, 28 (5):563-566.
[7] Brightbill HD, Libraty DH, Krutzik SR, et al. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science, 1999, 285 (5428):732-736.
[8] Kim J, Ochoa MT, Krutzik SR,et al. Activationof toll-like receptor 2 in acne triggers intlammatory cytokine responses. J Immunol, 2002,169(3):1535-1541.
[9] Adachi K, Tsutsui H, Kashiwamura S, et al. Plasmodium berghei in fection in mice induces liver injury by an IL-12-and toll-like receptor/myeloid differentiation factor 88-dependent tnechanism. J Immu nol, 2001, 167(10):5928-5934.
[10] Visintin A, Mazzoni A, Spitzer JH, et al. Regulation of Toll-like re ceptors in human monocytes and dendritic cells. J Immunol, 2001,166(1):249-255.
[11] Wagner H. Toll meets bacterial CpG-DNA. Immunity, 2001, 14 (5):499-502.
[12] Hirschfeld M, Weis JJ, Toshchakov V, et al. Signaling by toll-like re ceptor 2 and 4 agonists results in differential gene expression in murinemacrophages. Infect Immun, 2001,69 (3):1477-1482.
[13] Re F, Strominger JL. Toll-like receptor 2 (TLR2) and TLR4 differen tially activate human dendritic cells. J Biol Chem, 2001, 276 (40):37692-37699.
[14] Krieg AM. CpG DNA:a pathogenic factor in systemic lupus erythema tosus? J Clin Immunol, 1995, 15 (6):284-292.
[15] Leadbetter EA, Rifkin IR, Hohlbaum AM,et al. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like recep tors. Nature, 2002, 416(6881):603-607.
[16] Kawahara T, Kuwano Y, Teshima-Kondo S, et al. Toll-like receptor 4 regulates gastric pit cell responses to Helicobacter pylori infection. J Med Invest, 2001,48(3-4):190-197.
[17] Kurt-Jones EA, Popova L, Kwinn L, et al. Pattern recognition recep tors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol, 2000, 1 (5):398-401.
[18] Mambula SS, Sau K, Henneke P, et al. Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus. J Biol Chem, 2002, 277 (42):39320-39326.
[19] Bieback K, Lien E, Klagge IM, et al. Hemagglutinin protein of wildtype measles virus activates toll-like receptor 2 signaling. J Virol, 2002, 76 (17):8729-8736.
[20] Reiling N, Holscher C, Febrenbach A,et al. Cutting edge:toll-like receptor (TLR)2-and TLR4-mediated pathogen recognition in re sistance to airborne infection with Mycobacterium tuberculosis. J Im munol, 2002, 169 (7):3480-3484.
[21] Abel B, Thieblemont N, Quesniaux VJ,et al. Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice. J Immunol, 2002, 169(6):3155-3162,
[22] Ohashi K, Burkart V, Flohe S,et al. Cutting edge:heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 com plex. J Immunol, 2000, 164(2):558-561.
[23] Vabulas RM, Ahmad-Nejad P, Ghose S, et al. HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway J Biol Chem, 2002, 277(17):15107-15112.
[24] Frantz S, Kelly RA, Bourcier T. Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiac myocytes. J Biol Chem, 2001, 276(7):5197-5203.
[25] Li M, Carpio DF, Zheng Y, et al. An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue repair gene expression by necrotic cells. J Immunol, 2001, 166(12):7128-7135.
[26] Cario E, Podolsky DK. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflamma tory bowel disease. Infect Immun, 2000,68(12):7010-7017.
�������������
1����ӱ�,֣��.��м������������Toll������[J]. ����Ƥ���Բ�ѧ��־, 2008,34(2): 89-91
2��������,������.Toll�����������ѧ�о���չ[J]. ����Ƥ���Բ�ѧ��־, 2008,34(2): 92-94
3����ϼ,Ҧ־��.Toll�������뿹���������Ⱦ[J]. ����Ƥ���Բ�ѧ��־, 2008,34(5): 333-335
4������ ������ ����Ȫ ���� ��ǧ��.÷�����߰׽���4��Toll������2���򵥺������̬���о�[J]. ����Ƥ���Բ�ѧ��־, 2010,36(6): 306-308
5����ʥ ������.Toll������9��ϵͳ�Ժ���Ǵ�[J]. ����Ƥ���Բ�ѧ��־, 2006,32(6): 356-356
6����ͮ��.ϸ����ģʽʶ������NOD2������Ƥ�����е�����[J]. ����Ƥ���Բ�ѧ��־, 2007,33(2): 104-104
7������, ����ƽ.Toll�������ڿ�ϵͳ�������Ⱦ�е�����[J]. ����Ƥ���Բ�ѧ��־, 2004,30(4): 256-258
8��³����, ��С��, ֣��.CpG DNA��ϵͳ�Ժ���Ǵ������е�����[J]. ����Ƥ���Բ�ѧ��־, 2004,30(6): 360-362
9����ʢ, ����֥.Toll��������÷������[J]. ����Ƥ���Բ�ѧ��־, 2005,31(3): 139-141
10������, ������.Toll�������ijЩƤ�����Ĺ�ϵ[J]. ����Ƥ���Բ�ѧ��־, 2005,31(4): 259-261
11���ܱ���, �浤.Toll��������Ƥ������Ⱦ����[J]. ����Ƥ���Բ�ѧ��־, 2006,32(1): 51-53
12����ʥ, ������.Toll������9��ϵͳ�Ժ���Ǵ�[J]. ����Ƥ���Բ�ѧ��־, 2006,32(6): 356-358
13��������, ��־ǿ.ϸ����ģʽʶ������NOD2������Ƥ�����е�����[J]. ����Ƥ���Բ�ѧ��־, 2007,33(2): 104-106
14����ɯ ������.Toll������7��Ƥ�������о���չ[J]. ����Ƥ���Բ�ѧ��־, 2015,41(2): 118-120
15���׾� �ǽ��� ����.����ͷ��������Ⱦ�����������߷�Ӧ[J]. ����Ƥ���Բ�ѧ��־, 2015,41(2): 137-140

�������� (��ע��:��վʵ�������Ը�, �벻Ҫ������ѧ���޹ص�����!�������ݲ�����վ�۵�.)

Copyright 2008 by ����Ƥ���Բ�ѧ��־