|
��չ����
|
|
| ������Ϣ | |
 |
Supporting info |
|
PDFȫ�� |
|
[HTMLȫ��] |
|
����� |
| �����뷴�� | |
|
�������ù����� |
|
���� |
|
Email Alert |
|
���·��� |
|
���������Ϣ |
| ���Ĺؼ���������� | |
|
Ƥ֬��ϸ�� |
|
�ۼ��� |
|
� |
| ��������������� | |
|
��ǿ |
|
���� |
|
��¡�� |
| PubMed | |
|
Article by |
|
Article by |
|
Article by |
��Ƥ֬��ϸ�����ۼ��ع�ϵ���о���չ
��ǿ, ����, ��¡��
�й�ҽѧ��ѧԺ���й�Э��ҽ�ƴ�ѧƤ�����о���, �Ͼ�210042
�ۼ���������Ҫ�Ĵ�Ƥ֬�ٻ��Լ��ء����ۼ���������,��Ƥ֬��ϸ����������֬���Ƿ������ǰ����������Ƥ֬��ϸ���������ۼ������õİ�λ��,ͬʱҲ���кϳɻ����ۼ��ص�����,��ά��Ƥ�����ۼ�����̬����Ҫ��������������Ƥ֬��ϸ�����ۼ�������ù�ϵ���о���չ��
[2] Zouboulis CC. Human skin:an independent peripheral endocrine organ. Horm Res, 2000, 54(5-6):230-242.
[3] Fritsch M. Orfanos CE, Zouboulis CC. Sebocytes are the key regulators of androgen homeostasis in human skin. J Invest Dermatol,2001, 116(5):793-800.
[4] Dumont M, Luu-The V, Dupont E, et al. Characterization, expression, and immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase in human skin. J Invest Dermatol, 1992, 99(4):415-421.
[5] Thiboutot D, Knaggs H, Gilliland K, et al. Activity of 5-alphareductase and 17-beta-hydroxysteroid dehydrogenase in the infrainfundibulum of subjects with and without acne vulgaris. Dermatology, 1998, 196(1):38-42.
[6] Thiboutot D, Martin P, Volikos L,et al. Oxidative activity of the type 2 isozyme of 17beta-hydroxysteroid dehydrogenase (17beta-HSD)predominates in human sebaceous glands. J Invest Dermatol, 1998,111(3):390-395.
[7] Chen W, Zouboulis CC, Orfanos CE. et al. The 5 alpha-reductase system and its inhibitors. Recent development and its perspective in treating androgen-dependent skin disorders. Dermatology, 1996,193(3):177-184.
[8] Courchay G, Boyera N, Bernard BA, et al. Messenger RNA expression of steroidogenesis enzyme subtypes in the human pilosebaceous unit. Skin Pharmacol, 1996, 9 (3):169-176.
[9] Chen W, Zouboulis CC, Fritsch M, et al. Evidence of heterogeneity and quantitative differences of the type 1 5alpha-reductase expression in cultured human skin cells--evidence of its presence in melanocytes. J Invest Dermatol, 1998, 110(1):84-89.
[10] Deplewski D, Rosenfield RL. Role of hormones in pilosebaceous unit development. Endocr Rev, 2000, 21 (4):363-392.
[11] Miyake K, Ciletti N, Liao S,et al. Androgen receptor expression in the preputial gland and its sebocytes. J Invest Dermatol, 1994, 103(5):721-725.
[12] Rosenfield RL, Deplewski D, Kentsis A, et al. Mechanisms of androgen induction of sebocyte differentiation. Dermatology, 1998, 196(1):43-46.
[13] Rosenfield RL, Kentsis A, Deplewski D, et al. Rat preputial sebocyte differentiation involves peroxisome proliferator-activated receptors. J Invest Dermatol, 1999, 112 (2):226-232.
[14] Rook A, et al. Textbook of dermatology. 6th ed. miland:blackwell,1998. 1927-1940.
[15] Thiboutot D, Harris G, Iles V,et al. Activity of the type 1 5 alphareductase exhibits regional differences in isolated sebaceous glands and whole skin. J Invest Dermatol, 1995, 105(2):209-214.
[16] Akamatsu H, Zouboulis CC, Orfanos CE. Control of human sebocyte proliferation in vitro by testosterone and 5-alpha-dihydrotestosterone is dependent on the localization of the sebaceous glands. J Invest Dermatol, 1992, 99(4):509-511.
[17] Seiffert k, Fritsch M, Seltmann H, et al. Inhibition of 5��-reductase activith in immortalized human sebocytes and keratinocytes in vitro. J Invest Dermato1,2000,114 (4):811 (sbstract).
[18] Schmidt JB, Spona J, Huber J. Androgen receptor in hirsutism and acne. Gynecol Obstet Invest, 1986, 22 (4):206-211.
[19] Cunliffe WJ. The sebaceous gland and acne--40 years on. Dermatology, 1998, 196(1):9-15.