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[2] Greenhalgh DA, Rothnagel JA, Roop DR. Epidermis:an attractive target tissue for gene therapy. J Invest Dermatol, 1994, 103 (5 Suppl):S63-S69.
[3] Lin MT, Pulkkinen L, Uitto J, et al. The gene gun:current applications in cutaneous gene therapy. Int J Dermato, 2000, 39 (3):161-170.
[4] Huber M, Limat A, Wagner E, et al. Efficient in vitro transfection of human keratinocytes with an adenovirus-enhanced receptor-mediated system. J Invest Dermatol, 2000, 114 (4):661-666.
[5] Borradori L, Sonnenberg A. Structure and function of hemidesmosomes:more than simple adhesion complexes. J Invest Dermatol,1999, 112(4):411-418.
[6] Burgeson RE, Chiquet M, Deutzmann R, et al. A new nomenclature for the laminins. Matrix Biol, 1994, 14(3):209-211.
[7] Pulkkinen L, Uitto J. Hemidesmosomal variants of epidermolysis bullosa. Mutations in the alpha6beta4 integrin and the 180-kD bullous pemphigoid antigen/type ���� collagen genes. Exp Dermatol, 1998, 7(2-3):46-64.
[8] Gagnoux-Palacios L, Vailly J, Durand-Clement M, et al. Functional Re-expression of laminin-5 in laminin-gamma2-deficient human keratinocytes modifies cell morphology, motility, and adhesion. J Biol Chem, 1996, 271 (31):18437-18444.
[9] Gagnoux-Palacios L, Gache Y, Ortonne JP, et al. Hemidesmosome assembly assessed by expression of a wild-type integrin beta 4 cDNA in junctional epidermolysis bullosa keratinocytes. Lab Invest, 1997, 77(5):459-468.
[10] Robbins PB, Lin Q, Goodnough JB, et al. In vivo restoration of laminin 5 beta 3 expression and function in junctional epidermolysis bullosa. Proc Natl Acad Sci U S A, 2001,98(9):5193-5198.
[11] Bruckner-Tuderman L. Hereditary skin diseases of anchoring fibrils. JDermatol Sci, 1999, 20(2):122-133.
[12] Sawarnura D, Meng X, Itai K, et al. In vitro expression of full-length cDNA of type �� collagen:possibility of gene therapy for dystrophic epidermolysis bullosa (DEB). J Invest Dermatol, 1999,112 (4):551.
[13] Chen M, OToole EA, Muellenhoff M, et al. Development and characterization of a recombinant truncated type �� collagen "minigene".Implication for gene therapy of dystrophic epidermolysis bullosa. J Biol Chem, 2000, 275(32):24429-24435.
[14] Yang JM, Ahn KS, Cho MO, et al. Novel mutations of the transglutaminase 1 gene in lamellar ichthyosis. J Invest Dermatol, 2001, 117(2):214-218.
[15] Choate KA, Khavari PA. Direct cutaneous gene delivery in a human.genetic skin disease. Hum Gene Ther, 1997, 8 (14):1659-1665.
[16] Xu X, London E. The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation. Biochemistry, 2000, 39(5):843-849.
[17] Nemes Z, Demeny M, Marekov LN, et al. Cholesterol 3-sulfate interferes with cornified envelope assembly by diverting transglutaminase 1activity from the formation of cross-links and esters to the hydrolysis of glutamine. J Biol Chem, 2000, 275 (4):2636-2646.
[18] Jensen TG, Jensen UB, Jensen PK, et al. Correction of steroid sulfatase deficiency by gene transfer into basal cells of tissue-cultured epidermis from patients with recessive X-linked ichthyosis. Exp Cell Res,1993, 209(2):392-397.
[19] Freiberg RA, Choate KA, Deng H, et al. A model of corrective gene transfer in X-linked ichthyosis. Hum Mol Genet, 1997, 6 (6):927-933.
[20] Cleaver JE, Thompson LH, Richardson AS, et al. A summary of mutations in the UV-sensitive disorders:xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy. Hum Mutat, 1999, 14(1):9-22.
[21] Masutani C, Kusumoto R, Yamada A, et al. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta. Nature, 1999, 399(6737):700-704.
[22] Itoh T, Linn S, Kamide R, et al. Xeroderma pigmentosum variant heterozygotes show reduced levels of recovery of replicative DNA synthesis in the presence of caffeine after ultraviolet irradiation. J Invest Dermatol, 2000, 115(6):981-985.
[23] Zeng L, Quilliet X, Chevallier-Lagente O, et al. Retrovirus-mediated gene transfer corrects DNA repair defect of xeroderma pigmentosum cells of complementation groups A, B and C. Gene Ther, 1997, 4(10):1077-1084.
[24] Dumaz N, Drougard C, Quilliet X, et al. Recovery of the normal p53response after UV treatment in DNA repair-deficient fibroblasts by retroviral-mediated correction with the XPD gene. Carcinogenesis, 1998,19(9):1701-1704.
[25] Salido EC, Li XM, Yen PH, et al. Cloning and expression of the mouse pseudoautosomal steroid sulphatase gene (Sts). Nat Genet,1996, 13(1):83-86.
[26] Spirito F, Capt A, Ortonne J, et al. Mild junctional epidermolysis bullosa in dogs. A natural model for experimental gene therapy of the condition. J Invest Dermatol, 1999,113 (3):445
[27] Palazzi X, Marchal T, Chabanne L, et al. Inherited dystrophic epidermolysis bullosa in inbred dogs:A spontaneous animal model for somatic gene therapy. J Invest Dermatol, 2000, 115(1):135-137.
[28] van der Neut R, Cachaco AS, Thorsteinsdottir S, et al. Partial rescue of epithelial phenotype in integrin beta4 null mice by a keratin-5 promoter driven human integrin beta4 transgene. J Cell Sci, 1999, 112 (Pt 22):3911-3922.